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日用化学工业 ›› 2015, Vol. 45 ›› Issue (9): 518-522.doi: 10.13218/j.cnki.csdc.2015.09.009

• 专论与综述 • 上一篇    下一篇

二氢杨梅素结构及剂型修饰的研究进展

刘艳红1, 李驰荣2, 季丹丹1, 李丽1, 董银卯1, 祝钧1   

  1. 1.北京工商大学 理学院 中国化妆品协同创新中心,北京 100048;
    2.空军杭州航空医学鉴定训练中心,浙江 杭州 310007
  • 收稿日期:2015-05-07 修回日期:2015-08-28 出版日期:2015-09-22 发布日期:2019-04-10
  • 通讯作者: 祝 钧,教授,电话:13661302748,E-mail:zhujun@btbu.edu.cn。
  • 作者简介:刘艳红(1990-),女,硕士研究生,电话:18813090536,E-mail:liuyanhng_btbu@163.com。
  • 基金资助:
    校级协同创新中心——中国化妆品协同创新研究中心资助项目(19008001060)

Progress in research work field with respect to structural modification and formulation development of dihydromyricetin

LIU Yan-hong1, LI Chi-rong2, JI Dan-dan1, LI Li1, DONG Yin-mao1, ZHU Jun1   

  1. 1.China Cosmetic Collaborative Innovation Center,School of Science,Beijing Technology and Business University,Beijing 100048,China;
    2.Hangzhou Aciation Medical Appraisal and Training Center,Hangzhou,Zhejiang 310007,China
  • Received:2015-05-07 Revised:2015-08-28 Online:2015-09-22 Published:2019-04-10

摘要: 综述了二氢杨梅素结构修饰和剂型修饰的研究工作,介绍了金属离子螯合和酯化反应等结构修饰方法以及微乳液、脂质体、自乳化制剂、环糊精包裹、茶氨酸复合物和磷脂复合物等剂型修饰方法;讨论了修饰后物质的溶解度、抗氧化性和抑菌能力的变化;最后提出了二氢杨梅素结构及剂型修饰目前存在的问题、发展方向和应用前景。

关键词: 化妆品添加剂, 二氢杨梅素, 结构修饰, 剂型开发

Abstract: The research work with respect to structural modification and formulation development of dihydromyricetin was introduced,covering structural modification such as metal chelating and esterification et al.,as well as formulation development such as microemulsion,liposome,self-emulsifying agent,β-cyclodextrin encapsulation,theanine complexation and phospholipid complexation et al.The solubility,antioxidation activity and antibacterial capacity of the product after modification and development were discussed.Some existing problems,development trend and application prospects in this field were proposed.

Key words: additive of cosmetics, dihydromyricetin, structural modification, formulation development

中图分类号: 

  • TQ658