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日用化学工业（中英文）

日用化学工业 ›› 2017, Vol. 47 ›› Issue (9): 508-511.doi: 10.13218/j.cnki.csdc.2017.09.006

• 开发与应用 • 上一篇    下一篇

一种用于评价洗发水去屑功效的体外生物模型

陈默, 江丹, 黄亮, 张利萍   

  1. 广州立白企业集团有限公司,广东 广州 510170
  • 收稿日期:2017-04-05 发布日期:2019-03-20
  • 作者简介:陈 默(1988-),女,湖北宜昌人,硕士,工程师,电话:(020)81253367,E-mail:chenmo@liby.com.cn。

An in vitro model for evaluation of the anti-dandruff performance of hair care products

CHEN Mo, JIANG Dan, HUANG Liang, ZHANG Li-ping   

  1. Guangzhou Liby Enterprise Group Co.,Ltd.,Guangzhou,Guangdong 510170,China
  • Received:2017-04-05 Published:2019-03-20

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摘要： 以马拉色菌作为指示菌,建立了一种以猪皮为载体的生物模型。该生物模型可以用于评价头发护理产品的去屑功效。包含以下步骤:载体前处理;指示菌的接种;用洗发水处理猪皮模型,采用平板接触法进行抑菌效果测试;计算平板上马拉色菌的生长面积与平板面积之比作为有效指数P;以有效指数P评价产品的去屑功效。去屑剂评价结果表明,在0.1%~2.0%范围内,抑菌整体作用排序为BPT＞ZPT＞OCT。洗发水评价结果表明:1种洗发水无去屑功效;3种洗发水有去屑功效;2种洗发水有较强去屑功效。

关键词: 去屑洗发水, 马拉色菌, 体外模型

Abstract: An in vitro model for evaluation of the anti-dandruff performance of hair care products was established.In this model,Malassezia was used as indicator bacteria with pig skin as substrate.This model includes the following steps:pretreatment of the substrate;inoculation of indicator bacteria;measurement of the bacteriostatic efficacy by plate contact method;calculation of the effective index P;evaluation of the anti-dandruff performance by the effective index P.Three kinds of anti-dandruff agent,BPT,ZPT and OCT were tested with the model.Results show that the order for antibacterial efficacy of the anti-dandruff agents with mass fraction range of 0.1%~2.0% is BPT>ZPT>OCT.Evaluation results of hair shampoo from commercial market show that:one displays no anti-dandruff efficacy;three displays medium anti-dandruff efficacy;two displays strong anti-dandruff efficacy.

Key words: anti-dandruff shampoo, Malassezia, in vitro model

中图分类号: 

  • TQ658.3+3