欢迎访问《日用化学工业（中英文）》，今天是
日用化学工业（中英文）

日用化学工业 ›› 2021, Vol. 51 ›› Issue (12): 1278-1282.doi: 10.3969/j.issn.1001-1803.2021.12.016

• 分析与检测 • 上一篇    

液质联用法测定甘草组方化妆品中4种标志性成分

邓映明1,*(),陈媛1,邓美凌2,宋增炫1   

  1. 1.梅州市食品药品监督检验所,广东 梅州 514000
    2.嘉应学院 医学院,广东 梅州 514000
  • 收稿日期:2021-01-31 修回日期:2021-11-23 出版日期:2021-12-22 发布日期:2021-12-21
  • 通讯作者: 邓映明

Determination of four characteristic components in Glycyrrhiza uralensis based cosmetics by LC-MS method

Deng Yingming1,*(),Chen Yuan1,Deng Meiling2,Song Zengxuan1   

  1. 1. Meizhou Institute for Food and Drug Control, Meizhou, Guangdong 514000, China
    2. Medicine School of Jiaying College, Meizhou, Guangdong 514000, China
  • Received:2021-01-31 Revised:2021-11-23 Online:2021-12-22 Published:2021-12-21
  • Contact: Yingming Deng

RichHTML

15

PDF (PC)

337

赞

摘要：

建立液相色谱-质谱法测定宣称含有甘草成分的植物组方化妆品,以饱和氯化钠分散样品,乙腈超声提取,以0.1%甲酸水-乙腈作为流动相梯度洗脱,流速为0.4 mL/min,多反应监测（MRM）模式检测。4种成分在各自范围内线性关系良好,平均加样回收率85%~104%,RSD为1.1%~10.0%,方法检出限在1~15 ng/g之间;12批样品中检出符合率为41.6%。目前市售的植物组方中宣称甘草成分化妆品中,甘草成分检出率和检出含量较低,商家存在一定的概念营销,相关部门应加强监管。

关键词: 液质联用, 甘草, 化妆品

Abstract:

A LC-MS method was established for determination of botanical cosmetics claimed to contain ingredients from Glycyrrhiza uralensis. The sample was dispersed by saturated solution of sodium chloride and was ultrasonically extracted with acetonitrile. 0.1% formic acid water-acetonitrile was used as the mobile phase for gradient elution at a flow rate of 0.4 mL/min. Multiple reaction monitoring （MRM） mode was used for detection. The four components had good linear relationship within their respective range. The average recovery rate was 85%-104%, the RSD was 1.1%-10.0%, and the detection limit of the method was between 1 and 15 ng/g; 12 batches of samples were tested and the coincidence rate thereof was 41.6%. The test results indicate that the presence and the amount of ingredients from Glycyrrhiza uralensis are actually relatively low in as-claimed cosmetics. In other words, there are conceptual marketing and false publicity and thus relevant supervision should be strengthened.

Key words: LC-MS, Glycyrrhiza uralensis, cosmetics

中图分类号: 

  • TQ658