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日用化学工业（中英文）

日用化学工业（中英文） ›› 2025, Vol. 55 ›› Issue (7): 879-886.doi: 10.3969/j.issn.2097-2806.2025.07.008

• 开发与应用 • 上一篇    下一篇

石斛多糖/普鲁兰纳米纤维固态可吸收面膜的制备及功效研究

杨思佳1,刘慧1,吕永博2,*(),黄雨欣1,李姝静1,*()   

  1. 1.北京工商大学 轻工科学与工程学院，北京 100048
    2.北京炜烨创新科技有限公司，北京 100048
  • 收稿日期:2024-07-26 修回日期:2025-06-17 出版日期:2025-07-22 发布日期:2025-07-23
  • 基金资助:
    国家自然科学基金资助项目(22301012);北京市科协青年精英科学家资助项目(BYESS2024051);北京市教委研究与发展计划(KM202310011005);北京工商大学青年学者科研基金(QNJJ2022-23)

Preparation and efficacy study of dendrobium polysaccharide/purulan nanofiber solid absorbable mask

Sijia Yang1,Hui Liu1,Yongbo Lyu2,*(),Yuxin Huang1,Shujing Li1,*()   

  1. 1. School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China
    2. Beijing WeiYe Innovation Technology Co. Ltd., Beijing 100048, China
  • Received:2024-07-26 Revised:2025-06-17 Online:2025-07-22 Published:2025-07-23
  • Contact: *E-mail: lvyongbojtr@126.com;lishujing@th.btbu.edu.cn

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摘要：

制备了一款遇水溶解抗氧化干式面膜，将多糖良好的成膜性和水结合能力结合，为皮肤提供了良好的保湿效果。通过配制不同比例的石斛多糖/普鲁兰多糖复合溶液，采用静电纺丝技术制备石斛多糖/普鲁兰多糖，得到均匀连续的纳米纤维且纤维直径小于200 nm，在20 s内可以快速溶解，具有良好的亲水性和拉伸性。红外光谱表明石斛多糖和普鲁兰多糖分子间氢键形成。当质量分数为1.2%的石斛多糖和12%的普鲁兰多糖复配时，二者清除DPPH自由基和ABTS自由基的协同作用最强，溶解后的水溶液能够清除60%的DPPH自由基和85%的ABTS自由基，具有良好的抗氧化能力。由于整个纳米纤维膜中都是多糖的成分，具有一定的保水能力，能降低环境中的水分散失。通过细胞溶血实验评估其毒理安全性，证明了该纳米纤维无刺激性，作用温和，排异性低，保证与人体皮肤的高度亲和性，具备应用于面部护理的潜力。

关键词: 石斛多糖, 普鲁兰多糖, 复配, 保湿, 面膜

Abstract:

An antioxidant dry mask dissolved in water was prepared, combining the good film-forming property of polysaccharides with the ability to combine with water to provide a good moisturizing effect for the skin. By configuring different ratios of dendrobium polysaccharide/purulan polysaccharide composite solution, dendrobium polysaccharide/purulan polysaccharide was prepared by electrostatic spinning technology, and uniform and continuous nanofibers were obtained with a fiber diameter of less than 200 nm, which can be dissolved quickly within 20 s and has good hydrophilicity and tensile strength. Infrared spectroscopy indicates the formation of intermolecular hydrogen bonds between dendrobium polysaccharides and pullulan polysaccharides. When the concentrations of 1.2% dendrobium polysaccharide and 12% purulan polysaccharide are combined, the synergistic effect of the two in scavenging the DPPH radicals and the ABTS radicals are the strongest, and the aqueous solution can scavenge 60% of the DPPH radicals and 85% of the ABTS radicals after dissolution, with good antioxidant capacity. As the whole nanofiber membrane is composed of polysaccharides, it has a certain water retention capacity and can reduce water dissipation in the environment. The toxicological safety is assessed by cytolytic hemolysis experiment, which demonstrates that the nanofibers are non-irritating, mild activity, and low immunogenicity, ensuring high compatibility with human skin, and having the potential to be applied in facial treatments.

Key words: dendrobium polysaccharides, pullulan polysaccharide, compounding, moisturizing, facial masks

中图分类号: 

  • TQ658