电化学分析方法用于面膜中氯霉素现场快速检测

doi:10.3969/j.issn.2097-2806.2023.07.010

摘要/Abstract

摘要：

开发一种基于金纳米颗粒的便携式电化学传感器用于面膜中氯霉素现场快速分析。以电沉积的方式，采用沉积电位-0.6 V、沉积时间20 s，在便携式、可抛弃的丝网印刷电极表面沉积金纳米颗粒。结果显示，构建的负载金纳米颗粒的电化学传感器对氯霉素的电催化性能明显高于裸电极。实验考察了电解质溶液的pH，在较优条件下对不同浓度的氯霉素进行测定。结果显示，氯霉素浓度在0.02~0.5 mmol/L范围时，峰电流响应与氯霉素的浓度呈线性关系，方法的检出限为0.005 mmol/L。为了进一步评价方法的可行性，以市售面膜为实际样品进行添加回收实验。结果显示，三个添加水平下，氯霉素的添加回收率为106.01%~110.59%，相对标准偏差不大于3.66%（n=3）。结合手持式电化学工作站的无线蓝牙数据传输功能，可将现场检测结果实时传输至用户手机客户端，为面膜中氯霉素的现场快速筛查提供新的研究思路。

关键词: 氯霉素, 金纳米颗粒, 电化学传感器, 现场快速检测, 面膜

Abstract:

A portable electrochemical sensor based on gold nanoparticles has been developed for the on-site and rapid detection of chloramphenicol in facial masks. Herein, gold nanoparticles were electrochemically deposited on the surface of the portable and disposable screen-printed electrode with a deposition potential of -0.6 V and a deposition time of 20 s. Results show that the electrocatalytic performance of the chloramphenicol electrochemical sensor modified with gold nanoparticles is significantly enhanced compared with the bare electrode. The pH of the buffer solution was optimized and different concentrations of chloramphenicol were detected under optimal conditions. Results show that when the concentration of chloramphenicol is in the range of 0.02-0.5 mmol/L, the peak current signal is linearly related to the concentration of chloramphenicol, with the limit of detection of 0.005 mmol/L. In order to further evaluate the feasibility of this method, this paper took the commercially available facial masks as the real samples for the recovery experiment. Results show that the recoveries of chloramphenicol at the three spiked levels are from 106.01% to 110.59%, and the relative standard deviation is less than 3.66% （n=3）. Adopting the hand-held electrochemical workstation equipped with Bluetooth, the corresponding analysis data can be received wirelessly in real time on a smartphone, which provides a new research idea for the on-site and rapid detection of chloramphenicol in facial masks.

Key words: chloramphenicol, gold nanoparticles, electrochemical sensor, on-site and rapid detection, facial mask

中图分类号:

TQ658

王敏, 李萌月, 李晓熠, 刘琦, 赵华, 赵风年. 电化学分析方法用于面膜中氯霉素现场快速检测[J]. 日用化学工业（中英文）, 2023, 53(7): 802-807.

Wang Min, Li Mengyue, Li Xiaoyi, Liu Qi, Zhao Hua, Zhao Fengnian. On-site and rapid electrochemical method for chloramphenicol detection in facial masks[J]. China Surfactant Detergent & Cosmetics, 2023, 53(7): 802-807.

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样品	添加水平/（mmol/L）	测得值/（mmol/L）	平均回收率/%	RSD/%
面膜	0.05	0.053±0.002	106.01	3.66
	0.1	0.111±0.004	110.59	3.24
	0.2	0.216±0.003	107.98	1.31