根皮素在化妆品中的应用

doi:10.13218/j.cnki.csdc.2018.02.011

摘要/Abstract

摘要： 综述了根皮素的植物来源、制备方法、在化妆品中的作用以及应用现状。根皮素具有抗氧化、抗炎、防晒、促透皮吸收、美白、保湿、抑菌及防脱发作用,可用于开发功效型化妆品。

Abstract: The phloretin’s plants origin,preparation process,functions and application status in cosmetics were reviewed.Phloretin has lots of functions such as antioxidation,anti-inflammation,sunscreen,transdermal absorption promotion,skin whitening,moisturizing,antibacterial activity and anti alopecia.The phloretin has a promising prospect to be used in developing functional cosmetics.

Key words: phloretin, cosmetics, functional raw materials, application

中图分类号:

TQ658

崔树梅, 曹孟岑, 杨雪晨, 李梦杰, 何聪芬, 宋丽雅. 根皮素在化妆品中的应用[J]. 日用化学工业, 2018, 48(2): 113-118.

CUI Shu-mei, CAO Meng-cen, YANG Xue-chen, LI Meng-jie, HE Cong-fen, SONG Li-ya. Applications of phloretin in cosmetics[J]. China Surfactant Detergent & Cosmetics, 2018, 48(2): 113-118.

参考文献

[1] Antika L D,Lee E J,Kim Y H,et al.Dietary phlorizin enhances osteoblastogenic bone formation through enhancing β-catenin activity via GSK-3β inhibition in a model of senile osteoporosis [J].The Journal of Nutritional Biochemistry,2017,49:42-52.
[2] Lin C C,Chu C L,Ng C S,et al.Immunomodulation of phloretin by impairing dendritic cell activation and function [J].Food & Function,2014,5(5):997-1006.
[3] 曾俊,杨瑞山,蔡晓洋,等.俄色叶提取物对小鼠急性酒精性肝损伤的保护作用[J].食品工业科技,2017,38(13):311-314.
[4] 李燕,谢晓芳,李丹,等.俄色总黄酮对糖尿病的药理作用研究[J].中外医疗,2013,32(14):25-27.
[5] 夏冬梅,李敏,王道清,等.藏药俄色叶中根皮苷、根皮素含量分析[J].中国现代中药,2014,16(8):618-622.
[6] 杨素.苹果中多糖和黄酮类化合物肝损伤保护作用的药理活性研究[D].西安:陕西师范大学,2013.
[7] 乜兰春.苹果果实酚类和挥发性物质含量特征及其与果实品质关系的研究[D].保定:河北农业大学,2004.
[8] 赵艳敏,王皎,宋光明,等.苹果树枝和叶中根皮苷及根皮素含量变化研究[J].食品研究与开发,2013(7):95-98.
[9] Reis S F,Rai D K,Abughannam N.Water at room temperature as a solvent for the extraction of apple pomace phenolic compounds [J].Food Chemistry,2012,135(3):1991-1998.
[10] Rana S,Rana A,Gulati A,et al.RP-HPLC-DAD determination of phenolics in industrial apple pomace [J].Food Analytical Methods,2014,7(7):1424-1432.
[11] Zhang T,Wei X,Miao Z,et al.Screening for antioxidant and antibac-terial activities of phenolics from Golden Delicious apple pomace [J].Chemistry Central Journal,2016,10(1):47-55.
[12] Fromm M,Bayha S,Carle R,et al.Characterization and quantitation of low and high molecular weight phenolic compounds in apple seeds [J].Journal of Agricultural & Food Chemistry,2012,60(5):1232-1242.
[13] 国家苹果产业技术体系首席科学家办公室.2017年苹果产业发展趋势与建议[J].果农之友,2017(5):1-3.
[14] Dare A P,Tomes S,Cooney J M,et al.The role of enoyl reductase genes in phloridzin biosynthesis in apple [J].Plant Physiology & Biochemistry,2013,72:54-61.
[15] Jugdé H,Nguy D,Moller I,et al.Isolation and characterization of a novel glycosyltransferase that converts phloretin to phlorizin,a potent antioxidant in apple [J].Febs Journal,2010,275(15):3804-3814.
[16] 张金宏.苹果渣中游离酚和结合酚的提取及其功能特性的研究[D].杨凌:西北农林科技大学,2016.
[17] Karaman S,Tütem E,Baskan K S,et al.Comparison of antioxidant capacity and phenolic composition of peel and flesh of some apple varieties [J].Journal of the Science of Food & Agriculture,2013,93(4):867-875.
[18] 吕海涛,徐凯,姜华,等.正交试验法优选苹果树皮中根皮素的提取研究[J].食品研究与开发,2011,32(3):60-63.
[19] 梅建凤,李靓,易喻,等.紫变青霉生物转化根皮苷制备根皮素的研究[J].浙江工业大学学报,2016,44(6):660-664.
[20] 孟庆华,于晓霞,张海凤,等.天然黄酮类化合物清除自由基机理及其应用进展[J].云南民族大学学报(自然科学版),2012,21(2):79-83.
[21] Zuo A R,Yu Y Y,Shu Q L,et al.Hepatoprotective effects and antioxidant,antityrosinase activities of phloretin and phloretin isonicotinyl hydrazone [J].Journal of the Chinese Medical Association Jcma,2014,77(6):290-301.
[22] Chung M J,Sohng J K,Choi D J,et al.Inhibitory effect of phloretin and biochanin A on lg E-mediated allergic responses in rat basophilic leukemia RBL-2H3 cells [J].Life Sciences,2013,93(9):401-408.
[23] Limasser B,Doucen C,Dore J C.Effect of flavonoids on the release of reactive oxygenspecies by stimulated human neatrophils [J].Biochemical Pharmacology,1993,46(7):1257-1271.
[24] 孙玥,余燕影,曹树稳.阿魏酸、根皮素和水溶性V_E的抗氧化协同效应及其配方优化[J].食品科学,2012,33(3):33-38.
[25] 刘彩云,王卓娅,罗欣茹,等.根皮素抗氧化剂自微乳及微乳凝胶剂的研究[J].香料香精化妆品,2017(3):49-53.
[26] Wei Y,Zhang J,Memon A H,et al.Molecular model and in vitro antioxidant activity of a water-soluble and stable phloretin/hydroxypropyl-β-cyclodextrin inclusion complex [J].Journal of Molecular Liquids,2017,236:68-75.
[27] 李姝静,周自若,周威,等.根皮素与两种β-环糊精衍生物的包合作用及性质[J].食品科学,2017,38(7):11-16.
[28] 李芸,孙秋宁,杨蓉娅,等.舒缓特护面霜辅助治疗862例面部敏感性皮肤患者疗效观察[J].实用皮肤病学杂志,2015,8(1):85-88.
[29] Perez Carla,马立群.敏感性肌肤:解释和起源[C]//2006年中国化妆品学术研讨会论文集.上海:中国香精香料化妆品工业协会,2006:246-247.
[30] Barel A O,Paye M,Maibach H I.Handbook of cosmetic science and technology [M].Boca Raton:CRC Press,2014:1262-1263.
[31] Chang W T,Huang W C,Liou C J.Evaluation of the anti-inflammatory effects of phloretin and phlorizin in lipopolysaccharide-stimulated mouse macrophages [J].Food Chemistry,2012,134(2):972-979.
[32] Huang W C,Dai Y W,Peng H L,et al.Phloretin ameliorates chemokines and ICAM-1 expression via blocking of the NF-κB pathway in the TNF-α-induced HaCaT human keratinocytes [J].International Immunopharmacology,2015,27(1):32-37.
[33] Aliomrani M,Sepand M R,Mirzaei H R,et al.Effects of phloretin on oxidative and inflammatory reaction in rat model of cecal ligation and puncture induced sepsis [J].Daru Journal of Pharmaceutical Sciences,2016,24(1):1-8.
[34] Kum H,Roh K B,Shin S,et al.Evaluation of anti-acne properties of phloretin in vitro and in vivo [J].International Journal of Cosmetic Science,2016,38(1):85-92.
[35] 郑洪艳,庞建平,苏宁,等.天然植物紫外线防护效果研究[J].香料香精化妆品,2013(5):33-35.
[36] Oresajo C,Stephens T,Hino P D,et al.Protective effects of a topical antioxidant mixture containing vitamin C,ferulic acid,and phloretin against ultraviolet-induced photodamage in human skin [J].Journal of Cosmetic Dermatology,2010,7(4):290-297.
[37] Shin S,Kum H,Ryu D,et al.Protective effects of a new phloretin derivative against UVB-induced damage in skin cell model and human volunteers [J].International Journal of Molecular Sciences,2014,15(10):18919-18940.
[38] Przybylo M,Procek J,Hof M,et al.The alteration of lipid bilayer dynamics by phloretin and 6-ketocholestanol [J].Chemistry & Physics of Lipids,2014,178(2):38-44.
[39] 张旸,王庆伟,赵欢欢,等.复方根皮素乳膏中根皮素、藁本内酯体外透皮吸收研究[J].中国药师,2017,20(6):1038-1041.
[40] Valenta C,Cladera J,O'Shea P,et al.Effect of phloretin on the percutaneous absorption of lignocaine across human skin [J].Journal of Pharmaceutical Sciences,2001,90(4):485-492.
[41] Barreca D,Bellocco E,Laganà G,et al.Biochemical and antimicrobial activity of phloretin and its glycosilated derivatives present in apple and kumquat [J].Food Chemistry,2014,160:292-297.
[42] 张英.根皮素抑菌活性及抑菌机理的研究[D].西安:陕西师范大学,2016.
[43] 王建新,周忠,王建国.根皮素抑酪氨酸酶活性研究[J].香料香精化妆品,2002(2):4-5.
[44] 洪晓云.几种植物天然产物在化妆品上的应用[J].亚热带植物科学,2017,46(3):297-300.
[45] Duranton A.Modulating body/cranial hair growth with lipoxygenase/cyclooxygenase inhibitors:US5928654 [P].1999-07-27.