功能化离子液体[C3SO3Hnhm]HSO4催化合成苯并氧杂蒽

doi:10.13218/j.cnki.csdc.2018.11.005

摘要/Abstract

摘要： 无溶剂下以功能化酸性离子液体4-(3-磺丙基)吗啡啉硫酸氢盐([C₃SO₃Hnhm]HSO₄)为催化剂,催化β-萘酚和芳香醛合成苯并氧杂蒽。通过单因素试验和正交试验优化反应条件,并考察了该离子液体的重复使用性能。结果表明,当苯甲醛用量为0.005 mol,β-萘酚与苯甲醛摩尔比为2∶1,催化剂用量为苯甲醛的6%,100 ℃下反应10 min后苯并氧杂蒽的产率达到91%以上。[C₃SO₃Hnhm]HSO₄催化剂重复使用5次,其催化活性下降不明显,为苯并氧杂蒽类化合物的绿色合成提供了一种新方法。

关键词: 功能化酸性离子液体, 催化, 苯并氧杂蒽

Abstract: A solvent-free synthesis of benzoxanthene was operated,in which functionalized acidic ionic liquids,4-(3-propanesulfonic acid) morphinehydrogen sulfate [C₃SO₃Hnhm]HSO₄ were used as catalysts,andβ-naphthol and aromatic aldehyde were used as raw materials.The reaction conditions were optimized by the single factor experiment and orthogonal experiment,and the reusability of the ionic liquid catalyst was also studied.The results show that when the dosage of benzaldehyde is 0.005 mol,the molar ratio ofβ-naphthol to benzaldehyde is 2∶1,and the catalyst is in an amount corresponding to 6% of benzaldehyde,the yield can reach more than 91% after reaction for 10 min at 100 ℃.The catalytic activity of [C₃SO₃Hnhm]HSO₄ was not significantly reduced for being reused 5 times.This work has provided a new method for green synthesis of benzoxanthene compounds.

Key words: functionalized acidic ionic liquid, catalyze, benzoxanthene

中图分类号:

TQ423

汤小芳, 刘显明, 周思言, 李双. 功能化离子液体[C₃SO₃Hnhm]HSO₄催化合成苯并氧杂蒽[J]. 日用化学工业, 2018, 48(11): 627-631.

TANG Xiao-fang, LIU Xian-ming, ZHOU Si-yan, LI Shuang. Synthesis of benzoxanthene catalyzed by functionalized ionic liquids [C₃SO₃Hnhm]HSO₄[J]. China Surfactant Detergent & Cosmetics, 2018, 48(11): 627-631.

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功能化离子液体[C₃SO₃Hnhm]HSO₄催化合成苯并氧杂蒽

Synthesis of benzoxanthene catalyzed by functionalized ionic liquids [C₃SO₃Hnhm]HSO₄

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