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日用化学工业（中英文）

日用化学工业 ›› 2016, Vol. 46 ›› Issue (1): 58-60.doi: 10.13218/j.cnki.csdc.2016.01.012

• 分析与检测 • 上一篇    

顶空气相色谱-质谱联用法测定清洁类化妆品中的环氧丙烷

王琪慧1,李铭2,詹雪芳3   

  1. 1.成都师范学院 化学与生命科学学院,四川 成都 610041;
    2.成都产品质量检验研究院有限责任公司,四川 成都 610100;
    3.珀金埃尔默企业管理上海有限公司,四川 成都 610011
  • 出版日期:2016-01-22 发布日期:2016-01-22
  • 作者简介:王琪慧(1987-),女,讲师,博士,电话:15908184087,E-mail:guoguo515@126.com。
  • 基金资助:
    四川省教育厅重点资助项目(15ZA0336);成都师范学院人才引进专项(YJRC2015-10)

Determination of propylene oxide in cleaning cosmetics by HS-GC/MS

WANG Qi-hui1,LI Ming2,ZHAN Xue-fang3   

  1. 1.College of Chemistry and Life Sciences,Chengdu Normal University,Chengdu,Sichuan 610041,China;
    2.Chengdu Institute of Product Quality Inspection Co.,Ltd.,Chengdu,Sichuan 610100,China;
    3.Perkin Elmer Instruments Shanghai Co.,Ltd.,Chengdu,Sichuan 610011,China
  • Online:2016-01-22 Published:2016-01-22

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摘要： 建立了顶空气相色谱-质谱联用法(HS-GC/MS)测定清洁类化妆品中的环氧丙烷的方法。实验研究了平衡温度、平衡时间和盐类对环氧丙烷测定结果的影响。结果表明,较佳分析条件为称取试样20.0 g于50 mL的容量瓶中,加入10.0 g NaCl,加超纯水定容至50 mL,移取5 mL至22 mL顶空瓶中,超声混匀2 min,于80 ℃平衡10 min后测定;环氧丙烷在0.1~10 mg/L范围内线性良好(R2>0.999 9);该方法检出限为0.002 5 μg/g,定量下限为0.005 μg/g,样品加标平均回收率大于88%。

关键词: 化妆品, 环氧丙烷, 顶空气相色谱-质谱联用法

Abstract: A method for determination of propylene oxide in cleaning cosmetics by headspace gas chromatography/mass spectrometry (HS-GC/MS) was established.The influence of equilibrium temperature,equilibrium time and salts for propylene oxide measurement were investigated.Results showed that the better conditions are as follows:20.0 g of sample and 10.0 g of NaCl are added into 50 mL volumetric flask,and dilute with ultrapure water to 50 mL;transfer 5 mL of this solution to 22 mL headspace vial and mix with assistance of ultrasonic wave irradiation for 2 min,then the determination is to be carried out after the equilibrium at 80 ℃ for 10 min.The relationship between mass concentration and the corresponding peak area in the range of 0.1-10 mg/L shows good linearity (R2>0.999 9).The limit of detection is 0.002 5 μg/g and the limit of quantification is 0.005 μg/g.The average spiked recovery is >88%.

Key words: cosmetics, propylene oxide, HS-GC/MS

中图分类号: 

  • TQ658