石榴皮主要活性成分及其在化妆品中的应用研究进展

doi:10.3969/j.issn.2097-2806.2023.10.013

摘要/Abstract

摘要：

近些年来，随着人们对于化妆品的安全性的重视程度不断加深，植物提取物在化妆品中的应用也越加广泛。石榴皮作为传统的中药材，其中含有的丰富的鞣质类化合物、黄酮类化合物、多糖和有机酸等多种生物活性成分，体现出了它在化妆品中具有很好的应用价值。研究发现，石榴皮提取物可以在具有抗皱、防腐、美白、防晒等多种功效的化妆品中发挥作用。文章总结论述了石榴皮中含有的主要活性成分以及功效性研究，并讨论了石榴皮在化妆品中的应用现状以及未来的展望。

关键词: 石榴皮, 活性成分, 药理作用, 化妆品

Abstract:

In recent years, as people pay more attention to the safety of cosmetics, the application of plant extracts in cosmetics has become more and more extensive. Pomegranate peel, as a traditional Chinese herbal medicine, it has high security. Pomegranate peel is rich in tannins, flavonoids, polysaccharides, organic acids and other bioactive components, reflecting its good application value in cosmetics. It has many physiological and pharmacological activities, such as anti-oxidation, anti-bacterial, antimutagenic, anti-virus and anti-cancer. Through literature research, pomegranate peel extract is widely used in cosmetics with anti-wrinkle, anti-corrosion, whitening, sunscreen and other effects. However, studies have shown that pomegranate peel is slightly toxic, mainly because it contains alkaloids. The safety of pomegranate peel extract in cosmetics should be further studied. At present, there are few studies on the application of pomegranate peel extract in cosmetics instead of traditional preservatives, and its practical application as a preservative needs to be further studied. In addition, data on human efficacy evaluation of pomegranate peel extract in cosmetics with whitening and sunscreen effects are also scarce. Therefore, this paper summarizes and discusses the efficacy study and main active ingredients in pomegranate peel, and finally discusses the application status and future prospects of pomegranate peel in cosmetics. This paper is hoped to provide reference for the application of pomegranate peel extract in functional cosmetics.

Key words: pomegranate peel, active component, pharmacological effect, cosmetic

中图分类号:

TQ658

宋子欣, 孙倩茹, 方嘉璇, 王昌涛, 李萌, 王冬冬. 石榴皮主要活性成分及其在化妆品中的应用研究进展[J]. 日用化学工业（中英文）, 2023, 53(10): 1211-1219.

Song Zixin, Sun Qianru, Fang Jiaxuan, Wang Changtao, Li Meng, Wang Dongdong. Research progress on the application of main active ingredients of pomegranate peel in cosmetics[J]. China Surfactant Detergent & Cosmetics, 2023, 53(10): 1211-1219.

图/表 5

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作用对象	MIC/（mg/mL）	MBC/（mg/mL）	参考文献
金黄色葡萄球菌	7.8	62.5	[7]
枯草芽孢杆菌	0.22~0.45		[8]
痤疮丙酸杆菌	15.6×10^-3	>1	[9]
鼠伤寒沙门菌	10		[47]
铜绿假单胞菌	0.38~0.77		[8]
白色念珠菌	62.5		[25]

物质分类	化合物分类	具体物质
多酚类化合物	鞣质类化合物	鞣花酸、安石榴苷、安石榴林、没食子酸、鞣花单宁、没食子单宁、绿原酸等
多酚类化合物	黄酮类化合物	芦丁、槲皮素、槲皮苷、山奈酚、异鼠李素等
糖类化合物		果胶、鼠李糖、葡萄糖、半乳糖醛酸、甘露糖、木糖、半乳糖、岩藻糖、阿拉伯糖、葡萄糖醛酸等
其他	生物碱	石榴皮碱、异石榴皮碱、N-甲基异石榴皮碱、伪石榴皮碱等
	有机酸	熊果酸、苹果酸、白果酸等
	微量元素	钾、钙、镁、磷、钠、锌等