红花活性成分的提取及其改善皮肤微循环的功效评价

doi:10.3969/j.issn.1001-1803.2019.05.005

摘要/Abstract

摘要：

为探究红花及其与桃胶复合提取物对皮肤微循环的影响及化妆品原料应用前景。在提取了红花及其与桃胶复合物活性成分后,采用以激光多普勒检测技术为主,生物红外热成像等检测技术为辅的检测方法,对比受试者使用前后血流灌注量、红外温度、皮肤粗糙度、水分含量和水分散失量的数据变化,以及受试者皮肤状态变化情况。结果显示涂抹红花提取物及红花与桃胶的提取复合物7 d后,受试者的皮肤血流灌注量、面部温度、皮肤水分含量、水分散失量和皮肤鳞屑指数均有提高;红花提取物降低了细胞脱落数量,而红花和桃胶的复合提取物使细胞脱落数量增加。表明红花含有能够改善并促进皮肤微循环的活性物质,与桃胶制成复合物之后具有促进皮肤微循环的功效,可用作化妆品添加剂。

关键词: 红花, 红花和桃胶复合提取物, 活性成分, 皮肤微循环, 化妆品

Abstract:

In order to explore the effect of safflower and its compound extract with peach gum on skin microcirculation and the application prospect of cosmetics raw materials, after extracting the active components of safflower and its complex with peach gum, laser Doppler detection technique and biological infrared thermal imaging technique were adopted in order to compare the data changes of blood perfusion, infrared temperature, skin roughness, moisture content, transepidermal water loss and skin condition of the subjects before and after use. The results show that the amount of skin blood flow, facial temperature, skin moisture content, transepidermal water loss and skin scale index of the subjects are increased after 7 days with the application of safflower extract and the extract complex of safflower and peach gum. In addition, the extract of safflower decreases the amount of cell shedding, while the compound extract of safflower and peach gum increased the amount of cell shedding. It indicates that safflower contains an active substance capable of improving and promoting skin microcirculation, and has a function of promoting skin microcirculation after being compounded with peach gum, which can be used as a cosmetic additive.

Key words: safflower, compound extract of safflower and peach gum, active ingredient, skin microcirculation, cosmetic

中图分类号:

TQ658

聂园进泽,罗元,李欣洋,尹雅婷,易帆,孟宏. 红花活性成分的提取及其改善皮肤微循环的功效评价[J]. 日用化学工业, 2019, 49(5): 304-309.

NIE Yuan-jinze,LUO Yuan,LI Xin-yang,YIN Ya-ting,YI Fan,MENG Hong. Extraction of active components from Carthamus tinctorius and evaluation of its effect on improving skin microcirculation[J]. China Surfactant Detergent & Cosmetics, 2019, 49(5): 304-309.

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参考文献 13

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原料名称	w/%	实际添加质量/g	功效
红花提取物	5	4.00	功效物质
戊二醇	2	1.63	促渗剂
常温沸水	92	73.65	溶剂
MTI	0.12	0.096	防腐剂
AVC	1	0.85	增稠剂

原料名称	w/%	实际添加质量/g	功效
桃胶红花复合提取物	5	4.00	功效物质
戊二醇	2	1.62	促渗剂
常温沸水	92	73.60	溶剂
MTI	0.12	0.095	防腐剂
AVC	1	0.85	增稠剂

指标	红花（均值±标准差）		Sig值	红花桃胶复合物（均值±标准差）		Sig值
指标	使用前	使用后	Sig值	使用前	使用后	Sig值
多普勒	60.877 70	62.028 76	0.033^*	57.026 22	62.777 04	0.012^*
红外	30.593 13	31.060 47	0.033^*	30.451 11	30.725 03	0.296
水分含量	45.584 74	50.907 34	0.042^*	46.888 78	52.769 54	0.012^*
水分散失	11.434 39	12.210 55	0.006^**	10.689 74	10.660 95	0.029^*
SER	2.707 73	3.023 81	0.418	2.674 84	2.062 88	0.557
SESC	0.352 09	0.335 97	0.850	0.337 29	0.216 78	0.489

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