3种熊果苷的安全性评价进展及其化妆品法规管理现状

doi:10.3969/j.issn.2097-2806.2024.07.013

摘要/Abstract

摘要：

α-熊果苷、β-熊果苷、脱氧熊果苷具有良好的美白作用，但在一定条件下容易产生氢醌，有导致外源性褐黄病、白斑病、致敏、致癌等风险，因此其安全性备受国内外关注。文章通过整理总结近些年欧盟消费者安全科学委员会（SCCS）关于α-熊果苷、β-熊果苷、脱氧熊果苷的安全性评价报告，以及不同国家和地区化妆品法规对熊果苷的监管情况，以期了解熊果苷的安全性评价状况，为我国化妆品中熊果苷的使用及监管提供参考。

关键词: 熊果苷, 安全性评价, 美白, 化妆品法规

Abstract:

α-arbutin, β-arbutin and deoxyarbutin have good whitening effect, but they are easy to produce hydroquinone under certain conditions, which has the risk of exogenous ochronosis, achromodermia, sensitization, and carcinogenesis. So their safety has attracted much attention at home and abroad. The author summarizes the safety evaluation reports of α-arbutin, β-arbutin and deoxyarbutin by the Scientific Committee on Consumer Safety （SCCS） of the European Union in recent years, as well as the supervision situation of cosmetics regulations in different countries and regions, in order to understand the safety evaluation status of arbutin and provide references for the use and supervision of arbutin in cosmetics in China.

Key words: arbutin, safety evaluation, skin whitening, cosmetics regulations

中图分类号:

TQ658

吴姣娇, 章为, 王彦超, 裴新荣. 3种熊果苷的安全性评价进展及其化妆品法规管理现状[J]. 日用化学工业（中英文）, 2024, 54(7): 853-858.

Jiaojiao Wu, Wei Zhang, Yanchao Wang, Xinrong Pei. Safety evaluation progress of three kinds of arbutin and its current status in cosmetics regulations[J]. China Surfactant Detergent & Cosmetics, 2024, 54(7): 853-858.

图/表 1

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