化妆品经皮渗透研究进展——评价方法及促渗技术

doi:10.3969/j.issn.1001-1803.2020.11.010

Abstract

Abstract:

For the transdermal delivery system used in cosmetics, the common methods for promoting penetration have been listed, including chemical permeation-enhancing techniques, nanotechnology （nanoemulsions, nanocrystals, liposomes, niosomes, micelles, etc.）, physical permeation-enhancing techniques （iontophoresis, ultrasonic introduction, and microneedle） and biological permeability-promoting technology. The testing methods of transdermal absorption of cosmetics in vitro （in-vitro diffusion cell method, mathematical model, three-dimensional skin model, LC-MS, and Raman spectroscopy） have been briefly introduced, and the future transdermal penetration methods of cosmetics have been prospected.

Key words: skin permeation, evaluation method, 3D skin, liquid chromatography-mass spectrometry, transdermal enhancement technique

CLC Number:

TQ658

YANG Man-li,ZHOU Ming-yue,HU Xue-qing,CHEN Feng,HE Cong-fen,JIA Yan. Progress in research of skin permeability of cosmetics Evaluation method and enhancement technology[J].China Surfactant Detergent & Cosmetics, 2020, 50(11): 793-798.

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Progress in research of skin permeability of cosmetics Evaluation method and enhancement technology

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