以十二胺、丙烯酸甲酯、2,6-吡啶二甲酸为主要原料,经过加成、酰胺化、皂化等反应合成了一种酰胺型Gemini表面活性剂N,N’-双十二烷基-2,6-吡啶二酰胺丙酸钠（DLP-12）。经单因素变量考察得出该反应的最佳反应条件为：n（N-十二烷基-β-氨基丙酸甲酯）∶n（2,6-吡啶二甲酰氯）=2.4∶1,40 ℃下回流反应8 h。在此条件下DLP-12的产率为68.14%。性能测定的结果表明,在25,35和45 ℃时,此种新型Gemini表面活性剂的临界胶束浓度分别为9.1×10 -5,9.5×10 -5和9.7×10 -5mol/L,与之对应的表面张力分别为33.7,32.4和31.1 mN/m,最大表面过剩（Γmax）随着温度的升高而减小,临界堆积参数（CPP）的值表明表面活性剂自组装形态实现由层状结构向棒状结构过渡。25 ℃时,以液体石蜡和正辛烷作为油相所测得的乳化性能分别为277和252 s,罗氏泡沫高度为141 mm。
An amide Gemini surfactant N,N’-bis-dodecyl-2,6-pyridinium dimethylamide propionate sodium（DLP-12） was synthesized from dodecylamine, methyl acrylate, and 2, 6-pyridine-dicarboxylic acid by addition, amidation, and saponification reactions. By single factor experiments, the optimum reaction conditions for this reaction were: n（N-dodecyl-β-alanine-methyl ester）∶n（2, 6-pyridine-dicarboxylic acid）=2.4∶1, reflux reaction at 40 ℃ for 8 hours. Under these conditions, the yield of the final product was 68.14%. The results showed that the critical micelle concentrations of DLP-12 were 9.1×10 -5, 9.5×10 -5and 9.7×10 -5mol/L at 25, 35 and 45 ℃, respectively, and the corresponding surface tension were 33.7, 32.4 and 31.1 mN/m, respectively. The maximum surface excess concentration （Γmax） decreased with the increase of temperature. The value of the critical packing parameter （CPP） indicated the self-assembly morphology of surfactants in aqueous solution transformed from lamellar structure to rod-like structure. At 25 ℃, the emulsification properties measured with liquid paraffin and n-octane as the oil phase were 277 and 252 s, respectively, and the Roche foam height was 141 mm.
