牙膏去除外源性色斑功效评价方法的标准化研究

doi:10.3969/j.issn.2097-2806.2023.09.015

摘要/Abstract

摘要：

建立了一种评价牙膏去除外源性色斑功效的标准化体外测试方法。以牛牙作为底物，L^*a^*b^*色空间作为牙齿颜色的评价体系，通过染色-刷磨-测试的流程对牙膏样品的去除外源性色斑效果进行测定。对方法的关键参数进行系统优化，最终确定染色后L^*值[40，50]区间的牛牙，使用L8-Ⅱ刷磨仪配套平型的中毛牙刷，刷磨频率100 次/min进行600次刷磨等方法条件，建立了标准化的测试方法。结果表明该方法能有效区分不同配方样品间的差异，实验批次间相对标准偏差（RSD）小于10%，结果重现性较好。该方法具有成本低、实验周期短、操作简单等特点，为牙膏美白去渍的功效宣称提供可靠、科学的技术支撑。

关键词: 牙膏, 外源性色斑, 去除, 功效评价

Abstract:

A standardized in vitro method was established to evaluate the efficacy of toothpaste in extrinsic stain removal. Using bovine incisors as substrates and L^*a^*b^* color space as tooth color evaluating system, the removal effects of toothpaste samples on extrinsic stains were determined through the process of dyeing-brushing-testing. The critical parameters of the method were systematically optimized. A standardized method was established in which an L8-Ⅱ brushing machine was equipped with flat medium-bristle toothbrush and the dyed bovine incisors with L^* in the range of [40, 50] were chosen to be brushed for 600 times at 100 r/min. The results showed that the established method could effectively distinguish the difference between samples. The relative standard deviation （RSD） between experimental batches was less than 10% and the results were reproducible. This method was low-cost, short-period and easily operated. It might provide reliable and scientific test results for the efficacy of whitening and stain-removed toothpastes.

Key words: toothpaste, extrinsic stain, removal, efficacy evaluation

中图分类号:

TQ658

王继才, 简锐东, 谢宇, 陈晓斌, 周艺, 谭建华. 牙膏去除外源性色斑功效评价方法的标准化研究[J]. 日用化学工业（中英文）, 2023, 53(9): 1101-1107.

Wang Jicai, Jian Ruidong, Xie Yu, Chen Xiaobin, Zhou Yi, Tan Jianhua. Study on the standardization of evaluation for the efficacy of toothpaste in extrinsic stain removal[J]. China Surfactant Detergent & Cosmetics, 2023, 53(9): 1101-1107.

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	刷毛长度/mm	刷丝直径/mm	刷毛磨圆率/ %	毛束弯曲力/ N
标准牙刷	10.90	0.20	69	6.86
普通牙刷	10.90	0.22	73	6.20

L^*值范围	牙刷	L^*值（n=4）		ΔL^*值	显著性
L^*值范围	牙刷	刷牙前	刷牙后	ΔL^*值	显著性
30~40	普通牙刷	34.44±1.32	32.65±2.04	-1.80±0.75	NS
30~40	标准牙刷	34.69±0.88	33.80±1.27	-0.89±0.96	NS
40~50	普通牙刷	45.78±2.11	45.87±3.00	0.09±0.93	NS
40~50	标准牙刷	46.66±0.51	46.82±1.45	0.16±1.46	NS
50~60	普通牙刷	52.67±2.13	52.67±2.35	0.00±1.49	NS
50~60	标准牙刷	54.32±2.78	53.89±1.95	-0.43±1.71	NS

设备型号	L^*值（n=8）		ΔL^*值
设备型号	刷牙前	刷牙后	ΔL^*值
V8	47.88±1.71	59.02±1.98	11.14±1.69
L8-Ⅱ	48.02±1.36	60.05±3.20	12.03±2.30

L^*值范围	L^*值（n=8）		ΔL^*值
L^*值范围	刷牙前	刷牙后	ΔL^*值
30~40	31.92±1.67	44.76±1.82	12.85±1.20
40~50	44.45±0.50	57.37±2.78	12.92±2.90
50~60	55.20±2.05	61.32±3.09	6.12±1.88

生产批次	L^*值（n=8）		ΔL^*值
生产批次	刷牙前	刷牙后	ΔL^*值
1	43.20±1.53	54.23±1.57	11.03±2.20
2	43.22±1.31	53.95±1.10	10.73±0.91
3	42.95±1.28	55.58±4.20	12.63±3.86
4	43.31±1.16	56.70±3.36	13.39±3.32