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日用化学工业（中英文）

日用化学工业（中英文） ›› 2023, Vol. 53 ›› Issue (9): 1044-1050.doi: 10.3969/j.issn.2097-2806.2023.09.007

• 开发与应用 • 上一篇    下一篇

锰化合物抗氧化及保护头发光损伤功效评价

陈丽媛1,高合意1,2,唐金晶1,刘作华1,刘仁龙1,*()   

  1. 1.重庆大学 化学化工学院，重庆 401331
    2.广州栋方生物科技股份有限公司，广东 广州 510800
  • 收稿日期:2022-08-01 修回日期:2023-09-04 出版日期:2023-09-22 发布日期:2023-09-26
  • 基金资助:
    企事业单位委托科研项目(20201213)

Evaluation of antioxidant and protective effect against hair light damage of manganese compound

Chen Liyuan1,Gao Heyi1,2,Tang Jinjing1,Liu Zuohua1,Liu Renlong1,*()   

  1. 1. School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, China
    2. Guangzhou Ridgepole Biological Technology Co. Ltd., Guangzhou, Guangdong 510800, China
  • Received:2022-08-01 Revised:2023-09-04 Online:2023-09-22 Published:2023-09-26
  • Contact: * E-mail: lrl@cqu.edu.cn.

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摘要：

采用体外评价方法对甘氨酸锰（GlyMn）、硫酸锰（MnSO4）进行抗氧化及保护头发光损伤功效研究。通过测定GlyMn、MnSO4对超氧自由基和过氧化氢以及羟基自由基清除活性，考察GlyMn、MnSO4对活性氧自由基含量的影响，评价其抗氧化功效。采用模拟太阳光诱导头发光损伤的氧化损伤实验测试头发黑色素降解产生自由基含量，头发表面SEM表征评价锰化合物对头发的光保护作用。采用人体功效实验评价GlyMn、MnSO4洗发液的功能。结果表明，GlyMn、MnSO4对3种自由基均有明显的清除作用，其中3 mmol/L锰化合物能明显清除超氧自由基，清除能力相当于3 U/mL锰超氧化物歧化酶，当当锰化合物浓度在50 mmol/L时能明显降低头发中黑色素降解产生的自由基，能够有效保护头发光损伤，保护头发毛鳞片不受损害，表现出明显的抗氧化及头发光损伤保护功效。

关键词: 锰化合物, 自由基, 抗氧化, 头发光损伤

Abstract:

The antioxidation and hair protective effect of manganese glycine and manganese sulfate by experimental model in vitro are studied. The scavenging activities of GlyMn and MnSO4 on superoxide free radicals, hydrogen peroxide and hydroxyl free radicals were determined, and the content of GlyMn and MnSO4 on reactive oxygen free radicals was investigated to evaluate their antioxidant effects. The content of free radicals produced by the degradation of melanin in hair was measured by oxidative damage test, and the photoprotective effect of melanin on hair surface was evaluated by SEM. The function of GlyMn and MnSO4 shampoo was evaluated by human efficacy test. The results show that GlyMn and MnSO4 have significant scavenging effects on the three kinds of free radicals, among which 3 mmol/L manganese compound can significantly remove superoxide free radicals, which is equivalent to 3 U/mL manganese superoxide dismutase. When the concentration of manganese compound is 50 mmol/L, it can significantly reduce the free radicals produced by melanin degradation in hair. It can effectively protect the light damage of hair and protect the hair scales from damage, showing obvious antioxidant and light-damaged hair protection effect.

Key words: manganese compound, free radical, antioxidant, hair light damage

中图分类号: 

  • TQ658