Alg@TiO2微球稳定的Pickering乳液用做防晒乳成分的研究

doi:10.3969/j.issn.1001-1803.2022.03.001

摘要/Abstract

摘要：

为了开发一种兼具防晒功能和乳液稳定性的防晒乳配方,设计了一种负载二氧化钛纳米颗粒的海藻酸钙微球（Alg@TiO₂微球）来稳定Pickering乳液,用作防晒乳成分。考察了油水比和微球含量对Pickering乳液的影响,探究了乳液类型,并进行了长期保存稳定性测试。结果表明,Alg@TiO₂微球形状为球形,大小为2~6 μm;Alg@TiO₂微球中二氧化钛纳米颗粒含量为43%;微球与油水的三相接触角为120°;当油水比为1∶1,微球含量为3%（w/%）时,稳定的白油/水体系Pickering乳液为油包水型（W/O型）,经100 d室温保存后乳液状态保持稳定。通过紫外吸收实验,和包括市售防晒乳在内的其他3种防晒乳相比,该Pickering乳液具有优异的防晒性能。通过皮肤表面清洗实验,该Pickering乳液具有易清洗的特性。

关键词: 防晒乳, 二氧化钛纳米颗粒, Pickering乳液, 海藻酸钙微球

Abstract:

Sunscreen products can reduce the damage caused by UV rays, reducing tanning, inflammation and skin cancer. However, chemical sunscreen is more toxic, and the existing physical sunscreen is not stable and has poor sunscreening effect. Therefore, the development of a sunscreen formula with sunscreen function and emulsion stability has attracted extensive attention. In this work, a Pickering emulsion stabilized with calcium alginate microspheres loaded with titanium dioxide nanoparticles （Alg@TiO₂ microspheres） was designed to be used as a sunscreen component. By emulsification-gel method, the Pickering emulsion stabilized by hydrophobic TiO₂ nanoparticles was used as a template, and the internal aqueous phase was gelled. The TiO₂ nanoparticles were fixed on the surface of calcium alginate microspheres. The prepared microspheres were characterized by scanning electron microscopy, elemental analysis, thermogravimetric analysis and wettability. The effects of oil/water ratio and microsphere content on Pickering emulsion were investigated, and the type of emulsion was explored, and the long-term storage stability was tested. The results of SEM and elemental analysis showed that the Alg@TiO₂ microspheres were spherical in shape and contained TiO₂ nanoparticles on the surface, and the size of Alg@TiO₂ microspheres was approximately 2-6 μm. TGA results showed that the content of TiO₂ nanoparticles in Alg@TiO₂ microspheres was 43%. Wettability test showed that the three-phase contact angle between the microspheres and oil and water was 120°. When the oil/water ratio was 1∶1 and the mass fraction of microspheres was 3%, stable Pickering emulsion was formed with the largest emulsion volume fraction and the smallest droplet diameter. The emulsion type was water-in-oil type （W/O type）. The emulsion remained stable after 100 days at room temperature, facilitating the shelf life of the emulsion cosmetics. In UV absorption tests, the Pickering emulsion showed superior sunscreen performance compared with the other three types of sunscreens, including a commercially available sunscreen. This Pickering emulsion has been demonstrated to be easy to be cleaned as shown in skin surface cleaning experiments. The Pickering emulsion with high stability and excellent sunscreen performance as a sunscreen component is expected to promote the application of Pickering emulsions in daily chemical industry and promote the research and development of new cosmetics.

Key words: sunscreen, TiO₂ nanoparticle, Pickering emulsion, calcium alginate microsphere

中图分类号:

TQ658

谢鑫,王伟浩,刘环宇,孙梦梦,李沁园,贾露凡,孟涛. Alg@TiO₂微球稳定的Pickering乳液用做防晒乳成分的研究[J]. 日用化学工业, 2022, 52(3): 229-236.

Xie Xin,Wang Weihao,Liu Huanyu,Sun Mengmeng,Li Qinyuan,Jia Lufan,Meng Tao. Study on the Pickering emulsion stabilized by Alg@TiO₂ microspheres for sunscreen formulation[J]. China Surfactant Detergent & Cosmetics, 2022, 52(3): 229-236.

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编号	名称	成分及制备工艺
1	Alg@TiO₂微球稳定的Pickering乳液	油相：含3%的Alg@TiO₂微球的白油分散液;水相：实验室制备的RO水;以油水比1∶1混合,用手提式高速分散器以10 000 r/min乳化1 min
2	表面活性剂稳定的含TiO₂的乳液	油相：含适量表面活性剂的白油;水相：含3%未改性TiO₂的水分散液;油水比及乳化方法同上
3	含TiO₂的白油分散液	含3% TiO₂的白油分散液
4	含TiO₂的市售防晒乳

Alg@TiO₂微球稳定的Pickering乳液用做防晒乳成分的研究

Study on the Pickering emulsion stabilized by Alg@TiO₂ microspheres for sunscreen formulation

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