地骨皮化学成分及其生物学功效研究进展

doi:10.3969/j.issn.1001-1803.2021.05.013

Abstract

Abstract:

Cortex Lycii, the dried root bark of Lycium barbarum L. and Lycium chinense Mill. which belongs to Lycium, is a kind of traditional Chinese medicine with a long history of medicine and food and has high biological efficacy and medicinal value. It contains a variety of ingredients, including alkaloids, organic acids, glycosides, sterols, coumarins, anthraquinones, flavonoids, etc. Not only has a wealth of pharmacological activity, but also has the treatment of skin damage and beauty skin care effect. This article aimed at reviewing the recent literatures on its origin and distribution, the effective chemical constituents, pharmacological activity and mechanism, skin care effect and research status of Cortex Lycii so as to look forward to the application prospect of Cortex Lycii as a natural functional raw material in skin care and cosmetics industry.

Key words: Cortex Lycii, chemical constituent, pharmacological activity, skin care

CLC Number:

TQ658

XU He-ran,ZHAO Le,ZHANG Xiao-na,HUA Jing-lin,WANG Min,ZHAO Hua. Research progress on the chemical constituents and biological effects of Cortex Lycii[J].China Surfactant Detergent & Cosmetics, 2021, 51(5): 450-456.

Figures/Tables 5

Fig. 1

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Tab. 1

Tab. 2

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References 50

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序号	化学式	成分名称	参考文献
1	C₂₁H₃₂O₁₀	dihydrophaseic acid 3′-O-β-D-glucopyranoside （二氢红花菜豆酸3'-O-β-D-吡喃葡萄糖苷）	[6]
2	C₁₈H₂₆O₁₀	phenethyl alcohol xylopyranosyl-（1→6）-glucopyranoside （苯乙醇吡喃木糖基-（1→6）-吡喃葡萄糖苷）	[6]
3	C₁₉H₂₈O₁₀	2-phenylethyl-α-Larabinopyranosyl-（1→6）-β-D-glucopyranoside （2-苯乙基-α-L-吡喃阿拉伯糖基-（1→6）-β-D-吡喃葡萄糖苷）	[6]
4	C₁₃H₁₈O₈	Tachioside （它乔糖苷）	[6]
5	C₁₅H₂₀O₁₀	glucosyringic acid （丁香酸葡萄糖苷）	[6]
6	C₁₆H₁₈O₉	isoscoploletin-β-D-glucoside （异东莨菪苷）	[6]
7	C₁₆H₁₈O₉	Scoploletin （东莨菪苷）	[5,6]
8	C₁₈H₂₆O₁₂	digupigan A （地骨皮苷甲）	[6]
9	C₂₈H₃₈O₁₃	（+）-lyoniresinol-3α-O-β-D-glucopyranoside [（+）-南烛木树脂酚-3α-O-β-D-吡喃葡萄糖苷]	[6]
10	C₂₈H₃₈O₁₃	（-）-lyoniresinol-3α-O-β-D-glucopyranoside [（-）-南烛木树脂酚-3α-O-β-D-吡喃葡萄糖苷]	[6]

序号	化学式	成分名称	参考文献
1	C₁₈H₂₁NO₄	dihydro-feruloyltyramine	[3]
2	C₁₇H₁₈NO₂	N-trans-cinnamoyltyramine （N-反式桂皮酸酰对羟基苯乙胺）	[3]
3	C₁₇H₁₇NO₄	N-trans-coumaroyloctopamine	[3]
4	C₁₈H₁₉NO₄	N-cis-feruloyltyramine （N-顺式-对羟基苯乙基阿魏酰胺）	[3]
5	C₁₈H₁₉NO₄	N-trans-feruloyltyramine （反式-N-阿魏酰酪胺）	[3]
6	C₁₇H₁₇NO₄	N-trans-caffeoyltyramine （反式-N-对羟基苯乙基咖啡酰胺）	[3]
7	C₁₈H₂₁NO₄	N-（4-Hydroxyphenethyl）-4-hydroxybenzeneacrylamide （反式-N-对羟基香豆酰酪胺）	[3]
8	C₁₇H₁₉NO₄	dihydro-N-caffeoyltyramine （二氢咖啡酰酪胺）	[3,19]
9	C₂₈H₄₂N₄O₆	kukoamine A （地骨皮甲素）	[19]
10	C₂₈H₄₂N₄O₆	kukoamine B （地骨皮乙素）	[19]
11	C₁₃H₁₈N₂O₃	cis-N-caffeoyl putrescine （顺式咖啡酰丁二胺）	[19]
12	C₁₃H₁₈N₂O₃	trans-N-caffeoyl putrescine （反式咖啡酰丁二胺）	[19]
13	C₁₄H₂₀N₂O₃	N-isoferuloyl putrescine （异阿魏酰丁二胺）	[19]
14	C₁₈H₁₉NO₅	trans-N-faruloyloctopamine （反式阿魏酰章胺）	[19]
15	C₁₇H₁₇NO₄	trans-N-caffeoyltyramine （反式咖啡酰酪胺）	[19]
16	C₁₇H₁₇NO₄	cis-N-caffeoyltyramine （顺式咖啡酰酪胺）	[19]
17	C₁₇H₁₇NO₃	N-coumaroyl tyramine （香豆酰酪胺）	[19]

Research progress on the chemical constituents and biological effects of Cortex Lycii

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