Abstract:

In recent years, the incidence of disfiguring dermatosis such as acne vulgaris and atopic dermatitis has increased significantly, and its pathogenesis is closely related to abnormal sebaceous gland function. Sebaceous glands, located in the dermis, are important skin appendages. There are a large number of receptors on the sebaceous glands, which are regulated by a variety of factors. Abnormity in functions of sebaceous glands may cause a variety of skin problems. However, currently, domestic researchers have mostly paid attention to intercellular lipids, while the effects and mechanism of the sebum are not explored in depth, which causes lack of sufficient theoretical support in clinical application and the development of skin care products. In this paper, the mechanisms by which sebaceous glands maintain skin barrier function, participate in inflammation, and regulate senescence process and skin color from the perspective of skin care are summarized. Skin problems, detection methods and skin care ingredients related to sebaceous glands are systematically reviewed, aiming to provide references for solving relevant problems in skin care.

Key words: skin, sebaceous gland, sebum, skin care