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China Surfactant Detergent & Cosmetics ›› 2025, Vol. 55 ›› Issue (9): 1198-1206.doi: 10.3969/j.issn.2097-2806.2025.09.014

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Interaction mechanism and application of the aqueous mixtures of surfactants and proteins

Yutong Liu,Bingbing Yuan,Tiantian Han,Gong Chen,Yonghang Mu,Linhua Song*(),Zi Wang*()   

  1. College of Chemistry and Chemical Engineering, China University of Petroleum (East China), Qingdao, Shandong 266580, China
  • Received:2024-11-04 Revised:2025-08-14 Online:2025-09-22 Published:2025-10-11
  • Contact: *E-mail: ziwang@upc.edu.cn (Zi Wang); yanzfs@upc.edu.cn (Linhua Song). E-mail:yanzfs@upc.edu.cn;ziwang@upc.edu.cn

Abstract:

The research of the interaction mechanism between surfactants and proteins is of great significance for promoting the development of their applications across various fields. This review has focused on analyzing the behaviors of mixtures of surfactants and proteins both in bulk phase and at interfaces, with emphasis on the mechanisms involving electrostatic interactions, hydrophobic interactions, and competitive adsorption at interfaces, as well as the significant impact of regulating system parameters on these mechanisms. Furthermore, this review has combined surfactant-protein interactions with practical applications, elaborating on their specific roles in pharmaceutical industry, food industry, and daily chemical products. The specific molecular behaviors of surfactant-protein systems with varying factors and their relationships to applications were also summarized. This review might provide theoretical basis for the development of novel, efficient surfactants and for the regulation of related protein functionalities.

Key words: surfactant, protein, interaction mechanism, application

CLC Number: 

  • TQ423