TRP家族在舒缓化妆品中应用的专利技术分析

doi:10.3969/j.issn.2097-2806.2025.12.012

摘要/Abstract

摘要：

舒缓化妆品是化妆品领域长期以来的关注重点，而TRP相关通路是近年来舒缓化妆品领域最受瞩目的研究热点，文章综述了近年来舒缓化妆品领域TRP家族相关专利申请情况，总结了国内外技术主体专利申请及布局情况，并对典型主体的专利申请及布局情况进行了举例分析说明。此外，文章综述了舒缓化妆品领域中TRP家族相关原料整体应用情况及技术发展趋势，并对相关细分领域、细分人群、细分场景的整体技术情况进行了全面介绍。同时，文章以当前最受关注的TRPV1为例，总结了TRPV1当前的主要应用情况及典型的功效物质。文章从专利-技术全方面展示了TRP家族相关技术的发展趋势，总结了在技术开发及专利布局规划中需要注意的问题和方向，以期为我国相关技术主体在进行相关产品开发及专利布局时提供参考和帮助。

关键词: 舒缓, TRP, TRPV1, 专利, 化妆品

Abstract:

Soothing cosmetics have long been a hot topic in the cosmetics industry. TRP family, as an important pathway for achieving soothing effects, has been a research hotspot in the field of soothing cosmetics in recent years. Important pathways represented by TRPV1 have gradually become a research focus in the field of soothing. The article provides an overview and examples to illustrate the patent application of TRP family in the field of soothing cosmetics, and the patent layout of domestic and international main entities in recent years. In addition, the article introduces the overall application and technological development trends of TRP family related raw materials in the field of soothing cosmetics, and comprehensively introduces the overall technological situation of related segmented fields, segmented populations, and segmented scenarios. And the article summarizes the existing specific application scenarios and efficacy substances using TRPV1 as examples, which is currently the most prominent. In order to provide reference for relevant entities in China in product development and patent layout, the article comprehensively demonstrates the trends of TRP family related technologies from the perspective of patent analysis, and summarizes the issues and directions that need to be paid attention to in technology development and patent layout planning.

Key words: soothing, TRP, TRPV1, patent, cosmetics

中图分类号:

TQ658

刘月恒, 钱学宇, 吴迪, 黄惠, 李晨壹, 苏牧楠. TRP家族在舒缓化妆品中应用的专利技术分析[J]. 日用化学工业（中英文）, 2025, 55(12): 1589-1599.

Yueheng Liu, Xueyu Qian, Di Wu, Hui Huang, Chenyi Li, Munan Su. Analysis of patent technology of TRP family application in soothing cosmetics[J]. China Surfactant Detergent & Cosmetics, 2025, 55(12): 1589-1599.

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通路	TRPV1（↓）			TRPM8（↑）	TRPV1
当前申请人	审中	失效	有效	审中	有效
贝泰妮	3	0	1	0	0
梁天晓	1	7	0	0	0
诺德溯源（广州）	0	1	6	0	0
山东福瑞达	1	0	3	0	0
上海珈凯生物	1	1	1	0	1
上海梦希生物	0	4	0	0	0
上海皮宝生物	0	0	3	0	0
深圳市维琪	3	0	1	0	0
水羊化妆品	2	0	2	1	0
西安绿天生物	3	0	1	0	0

	总计数量/项	抑制			激活			评价方法
	总计数量/项	经实验验证	原料/产品介绍	总计	经实验验证	原料/产品介绍	总计	评价方法
TRPV1	337	166	158	324	0	1	1	10
TRPM8	56	0	0	0	28	24	52	3
TRPA1	54	30	7	37	5	0	5	13
TRPV4	26	5	1	6	9	7	16	4
TRPV3	20	10	1	11	7	1	8	1
TRPV2	1	1	0	1	0	0	0	0
TRPC6	1	0	0	0	0	1	1	0
TRPM2	1	1	0	1	0	0	0	0
TRPM5	1	0	0	0	1	0	1	0
TRPM6	1	1	0	1	0	0	0	0
TRPM7	1	1	0	1	0	0	0	0