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日用化学工业 ›› 2014, Vol. 44 ›› Issue (8): 456-459.doi: 10.13218/j.cnki.csdc.2014.08.102

• 开发与应用 • 上一篇    下一篇

松口蘑活性物提取工艺研究及其安全功效评价

邓影妹, 赵华   

  1. 北京工商大学 中国化妆品研究中心 北京市植物资源研究开发重点实验室,北京 100048
  • 收稿日期:2014-05-16 发布日期:2019-04-08
  • 通讯作者: 赵 华,电话:(010)68984949,E-mail:zhaoh@btbu.edu.cn。
  • 作者简介:邓影妹(1988-),女,河北人,硕士研究生,E-mail:dengyingmei2013@126.com。

Extraction technology of Tricholoma matsutake Sing and evaluation for its safety and efficacy on human body

DENG Ying-mei, ZHAO Hua   

  1. Beijing Key Laboratory of Plant Research Development,Chinese Cosmetics Research Center, Beijing Technology and Business University,Beijing 100048,China
  • Received:2014-05-16 Published:2019-04-08

摘要: 对松口蘑提取工艺进行优化,并测定提取物中总黄酮、总多酚及总多糖含量。结果表明,在溶剂为体积分数70%乙醇水溶液,料液比1:20,提取时间2 h条件下,提取物对酪氨酸酶活性的抑制率达59.71%,总黄酮、总多酚和总多糖质量分数分别为0.720 mg·g-1,0.026 mg·g-1和11.84%。安全性实验结果表明:松口蘑提取物添加量不大于4%时,红细胞溶血率不高于4.31%;将松口蘑膏霜样品进行斑贴试验,结果呈阴性。人体美白功效试验结果表明,松口蘑膏霜样品能够抑制黑色素沉着和提升皮肤亮度,具有美白功效。

关键词: 化妆品添加剂, 松口蘑提取物, 安全性, 人体功效

Abstract: Extraction technology of Tricholoma matsutake Sing was optimized and the content of its total flavonoids,total polyphenols and total polysaccharides were determined.Results showed that,under extraction conditions as: solvent,ethanol aqueous solution with volumetric concentration 70%;solid-liquid ratio,1:20;extraction time,2 h;its inhibition efficacy on tyrosinase achieves 59.71%.Content of total flavonoids,total polyphenols and total polysaccharides in the Tricholoma matsutake Sing were determined as 0.720 mg·g-1,0.026 mg·g-1 and 11.84% respectively.Safety tests results showed that,as the addition amount of the Tricholoma matsutake Sing extract is not more than 4%,hemolysis of blood red cell will be not higher than 4.31%.Patch test results of the cosmetic cream product containing Tricholoma matsutake Sing shows negative.Via the whitening efficacy tests,the cosmetic cream product containing the Tricholoma matsutake Sing extract shows efficacy for inhibition of melanin pigmentation as well as improvement of brightness and whitening of human body skin.

Key words: additive of cosmetics, Tricholoma matsutake Sing extract, safety, efficacy on human body

中图分类号: 

  • TQ658