China Surfactant Detergent & Cosmetics ›› 2025, Vol. 55 ›› Issue (12): 1589-1599.doi: 10.3969/j.issn.2097-2806.2025.12.012
• Reviews • Previous Articles Next Articles
Yueheng Liu*(
),Xueyu Qian,Di Wu,Hui Huang,Chenyi Li,Munan Su
Received:2024-12-18
Revised:2025-12-22
Online:2025-12-22
Published:2026-01-23
Contact:
*E-mail: CLC Number:
Yueheng Liu, Xueyu Qian, Di Wu, Hui Huang, Chenyi Li, Munan Su. Analysis of patent technology of TRP family application in soothing cosmetics[J].China Surfactant Detergent & Cosmetics, 2025, 55(12): 1589-1599.
Tab. 1
Patent application status of top 10 Chinese applicants in different channels (patent application quantity/item)"
| 通路 | TRPV1(↓) | TRPM8(↑) | TRPV1 | ||
|---|---|---|---|---|---|
| 当前申请人 | 审中 | 失效 | 有效 | 审中 | 有效 |
| 贝泰妮 | 3 | 0 | 1 | 0 | 0 |
| 梁天晓 | 1 | 7 | 0 | 0 | 0 |
| 诺德溯源(广州) | 0 | 1 | 6 | 0 | 0 |
| 山东福瑞达 | 1 | 0 | 3 | 0 | 0 |
| 上海珈凯生物 | 1 | 1 | 1 | 0 | 1 |
| 上海梦希生物 | 0 | 4 | 0 | 0 | 0 |
| 上海皮宝生物 | 0 | 0 | 3 | 0 | 0 |
| 深圳市维琪 | 3 | 0 | 1 | 0 | 0 |
| 水羊化妆品 | 2 | 0 | 2 | 1 | 0 |
| 西安绿天生物 | 3 | 0 | 1 | 0 | 0 |
Tab. 2
Distribution of targets-patent quantity for soothing cosmetics-TRP (items)"
| 总计数量/项 | 抑制 | 激活 | 评价方法 | |||||
|---|---|---|---|---|---|---|---|---|
| 经实验验证 | 原料/产品介绍 | 总计 | 经实验验证 | 原料/产品介绍 | 总计 | |||
| TRPV1 | 337 | 166 | 158 | 324 | 0 | 1 | 1 | 10 |
| TRPM8 | 56 | 0 | 0 | 0 | 28 | 24 | 52 | 3 |
| TRPA1 | 54 | 30 | 7 | 37 | 5 | 0 | 5 | 13 |
| TRPV4 | 26 | 5 | 1 | 6 | 9 | 7 | 16 | 4 |
| TRPV3 | 20 | 10 | 1 | 11 | 7 | 1 | 8 | 1 |
| TRPV2 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
| TRPC6 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
| TRPM2 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
| TRPM5 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
| TRPM6 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
| TRPM7 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
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