当期目录

2016年, 第46卷, 第4期　刊出日期：2016-04-22 上一期    下一期

基础研究

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基于HP-β-CD修正光谱法检测SDBS/OP-10二元复配体系 Quantitative determination of SDBS and OP-10 binary blend system based on the revised spectrum induced by HP-β-CD 石东坡, 尹先清, 陈武, 郑延成, 李赓 2016 (4):  183-188.  doi: 10.13218/j.cnki.csdc.2016.04.001 摘要 ( 266 )   PDF(811KB) ( 311 )   十二烷基苯磺酸钠(SDBS)和辛基酚聚氧乙烯醚(OP-10)之间的相互作用,能对复配体系中二者的检测产生明显影响。实验结果表明,在水溶液中OP-10能对同步荧光光谱法测定SDBS的表观cmc及荧光强度产生显著影响:当OP-10的浓度从0增加到0.500,1.000和2.000 mmol/L时,SDBS的表观cmc由1.183 mmol/L分别降低至1.011,0.861和0.658 mmol/L;增加OP-10的浓度还将导致SDBS的同步荧光强度逐渐增大。SDBS也会对比色法检测OP-10产生显著影响。按SDBS的摩尔计量比加入1∶1的羟丙基-β-环糊精(HP-β-CD),能明显降低SDBS和OP-10间的相互作用,二元复配溶液中SDBS和OP-10的回收率分别由80.2%~105.2%和65.4%~93.1%变化至101.1%~101.4%和101.4%~102.6%,SDBS和OP-10的检测准确度均显著提高。Job’s实验及FT-IR分析表明,SDBS分子进入HP-β-CD分子的内腔进而形成1∶1的包结物,是降低各种相互协同作用对检测SDBS和OP-10产生影响的主因。 The interaction between sodium dodecyl benzene sulfonate (SDBS) and ethoxylated octylphenol (OP-10) could have a significant impact on the quantitative determination of SDBS/OP-10 binary blend in aqueous solution.Experimental results indicated that the apparent critical micelle concentration (cmc) values and the fluorescence intensities of SDBS measured by synchronous fluorescence spectrometry could be greatly changed because of the existence of OP-10.The cmc values of SDBS reduce from 1.183 mmol/L to 1.011,0.861 and 0.658 mmol/L when the concentrations of OP-10 increase from 0 to 0.500,1.000 and 2.000 mmol/L in water respectively,and the fluorescence intensities of SDBS would be increased with the increasing concentration of OP-10.On the other hand,the existence of SDBS could also have a significant impact on the quantitative analysis of OP-10 in aqueous solution by chemical colorimetry.The results indicated that the interaction between SDBS and OP-10 could be greatly reduced by adding 1∶1 hydroxypropyl-β-cyclodextrin (HP-β-CD) according to the molar amount of SDBS,thus,the recovery rates of SDBS and OP-10 change from 80.2%-105.2% and 65.4%-93.1% to 101.1%-101.4% and 101.4%-102.6% respectively,which showed that the measurement veracity of SDBS and OP-10 in SDBS/OP-10 binary blend has been greatly improved.The experimental results of Job’s test and FT-IR analysis exhibited that the interaction between SDBS and OP-10 could be greatly reduced because of the formation of HP-β-CD/SDBS inclusion compound with molar ratio of 1∶1. 参考文献 | 相关文章 | 计量指标

科技讲座

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氟表面活性剂和氟聚合物(Ⅳ) ——PFOS问题的应对策略 Fluorinated surfactants and fluoropolymers (Ⅳ) Strategy for PFOS problems 邢航,贾旭宏,肖进新 2016 (4):  189-194.  doi: 10.13218/j.cnki.csdc.2016.04.002 摘要 ( 275 )   PDF(727KB) ( 569 )   碳氟链的特殊性质决定了某些氟烷基化合物在目前很多特殊场合是不可替代的,但传统的PFOS引发的环境及安全问题亟待解决。讨论了PFOS问题的若干解决办法,包括探索其降解方法或分离及循环使用方法或降低PFOS的使用浓度至规定限量以下,而根本解决之道还是寻求PFOS的替代品。从几个角度讨论了PFOS的替代品并对其应用的合理性进行了分析。 Some fluorinated alkyl substances are necessary in nowadays many fields because of the special properties of fluorocarbon chains.However,the traditional environmental and toxicity problems of PFOS have to be resolved.Several ways for solving the concerning problems were discussed,including the possibilities for degradation,separation and recycling use,as well as reducing the concentration in the application to be lower than the specified limit.The most reliable one is to obtain substitute for the PFOS.Several kinds of substitute were introduced and their rationality of application was also discussed. 参考文献 | 相关文章 | 计量指标

开发与应用

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一种新型吡啶Gemini表面活性剂的合成及表面活性 Synthesis and surface activity of a novel Gemini pyridinium surfactant 郝俊生,王攀,张越,张永斌 2016 (4):  195-199.  doi: 10.13218/j.cnki.csdc.2016.04.003 摘要 ( 272 )   PDF(809KB) ( 304 )   以3-氨基吡啶和固体光气为原料,一锅法合成中间体1,3-二(3-吡啶基)脲,然后再与溴代十二烷进行季铵化反应,生成了新型的吡啶阳离子Gemini表面活性剂。通过单因素试验法优化了反应条件,得到较佳工艺条件为:n(3-氨基吡啶)∶n(固体光气)=5∶1,二氯甲烷作反应溶剂,反应5 h,得到产率为78%的中间体;n(中间体)∶n(溴代十二烷)=1∶10,110 ℃反应5 h,得到产率为90%的吡啶Gemini表面活性剂。通过FT-IR,1H NMR,13C NMR和ESI-MS对所得产物的结构进行了表征,并对其表面活性进行了研究。结果表明,该Gemini表面活性剂的临界胶束浓度(cmc)为1.67×10-4 mol/L,γcmc为30.7 mN/m。 The intermediate 1,3-di(3-pyridyl)urea was synthesized by the reaction of 3-aminopyridine and triphosgene.The optimized conditions for the reaction were found as follows:reaction solvent,methylene chloride;reaction time,5 h;mole ratio of 3-aminopyridine and triphosgene,5∶1.The yield is 78%.Then the intermediate reacted with bromododecane to produce a new type of Gemini pyridinium surfactant.The optimized conditions were identified as follows:reaction time,5 h;reaction temperature,110 ℃;mole ratio of the intermediate and bromododecane,1∶10.The yield is 90 %.The structure of the target product was characterized by FT-IR,1H NMR,13C NMR and ESI-MS.The surface tension of the product was measured as cmc value of 1.67×10-4 mol/L and γcmc of 30.7 mN/m. 参考文献 | 相关文章 | 计量指标

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月桂酰胺丙基氧化胺的吸附性能研究 Adsorption performance of lauramidopropyl amine oxide 张雯,葛际江,张贵才,王洋,宋开飞 2016 (4):  200-203.  doi: 10.13218/j.cnki.csdc.2016.04.004 摘要 ( 280 )   PDF(684KB) ( 421 )   合成了月桂酰胺丙基氧化胺(LAO),利用pH计测定了其等电点,利用高效液相色谱仪、表面张力仪分别研究了pH和温度等因素对其在石英砂表面吸附性能的影响以及其对十二烷-水-玻璃三相接触角的影响。结果表明:LAO的等电点在pH＝9左右;随着pH升高,LAO水溶液的临界胶束浓度降低;随着温度和pH的升高,LAO在石英砂表面的吸附量下降;随着LAO质量浓度的增加,十二烷-水-玻璃三相接触角先增加后减小至平衡;LAO在石英砂表面的吸附为双层吸附。 Lauramidopropyl amine oxide (LAO) was synthesized.The isoelectric point of LAO,the effect of pH and temperature on adsorption behavior of LAO on the surface of the quartz sand and the effect of LAO on contact angle of the dodecane/water/glass were systematically investigated by using pH meter,high performance liquid chromatograph and surface tension meter respectively.Results showed that the isoelectric point of LAO is close to pH of 9;the increase of pH causes the critical micelle concentration of LAO to decrease;the increase of temperature and pH causes the adsorption of LAO on the surface of quartz sand to decrease;the contact angle of the dodecane/water/glass increases firstly,and then decreases to balance by increasing the mass concentration of LAO;the adsorption mechanism of LAO on the surface of quartz sand is double layer adsorption. 参考文献 | 相关文章 | 计量指标

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甜菜碱表面活性剂的合成及其胶束催化乙酸酯水解的研究 Synthesis of betaine surfactant and its micellar catalysis action on alkaline hydrolysis of acetic esters 周杨,潘忠稳,陈赓,孙硕 2016 (4):  204-207.  doi: 10.13218/j.cnki.csdc.2016.04.005 摘要 ( 236 )   PDF(850KB) ( 293 )   实验合成了2种甜菜碱表面活性剂C-12和C-16,并在25 ℃的条件下,采用电导率法研究了乙酸乙酯和乙酸戊酯在C-12和C-16胶束溶液中的碱性水解反应。无表面活性剂时,乙酸乙酯水解速率常数k为0.111 L/(mol·s),乙酸戊酯的k为0.082 L/(mol·s)。当表面活性剂浓度为8×10-4 mol/L时,C-12催化下乙酸乙酯的k为0.183 L/(mol·s),乙酸戊酯的k为0.112 L/(mol·s);而C-16催化下乙酸乙酯的k为0.226 L/(mol·s),乙酸戊酯的k为0.135 L/(mol·s)。结果表明,C-12和C-16对乙酸酯的水解均有催化作用,相同条件下,乙酸乙酯水解速度快于乙酸戊酯。 Two kinds of betaine surfactant (C-12 and C-16) were synthesized in laboratory.Alkaline hydrolysis of ethyl acetate and amyl acetate,under 25 ℃ in micellar solution of C-12 and C-16 separately was studied in accordance with electric conductivity method.In case without use of surfactant,the hydrolysis rate constant (k) of ethyl acetate and amyl acetate is 0.111 and 0.082 L/(mol·s) respectively.In case surfactant is used and the concentration of surfactant is 8×10-4 mol/L,the k of ethyl acetate and amyl acetate to C-12 is 0.183 and 0.112 L/(mol·s) respectively,and the corresponding to C-16 is 0.226 and 0.135 L/(mol·s) respectively.The results indicated that C-12 and C-16 can catalyze the hydrolysis of acetates.Under same conditions,the rate of hydrolysis for ethyl acetate is faster than amyl acetate. 参考文献 | 相关文章 | 计量指标

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复配表面活性剂-模拟油-水体系的界面张力研究 Study on interfacial tension of mimetic oil and water system with blend surfactants 刘宣池,张亚刚,于二雷,崔平正,吾满江·艾力 2016 (4):  208-211.  doi: 10.13218/j.cnki.csdc.2016.04.006 摘要 ( 365 )   PDF(949KB) ( 751 )   在45 ℃下测定了不同类型表面活性剂(阴离子、阳离子和非离子表面活性剂以及高分子双子表面活性剂、非对称两性双子表面活性剂)与煤油-水体系的界面张力,发现非离子表面活性剂效果最好,界面张力可达0.690 mN/m。采用聚乙二醇辛基苯基醚与其他类型的表面活性剂进行两两复配,考察复配表面活性剂的种类、质量比、总质量浓度对模拟油-水体系界面张力的影响。发现聚乙二醇辛基苯基醚与非对称两性双子表面活性剂C15EC-S-C16以质量比7∶3进行复配,总质量浓度为50 g/L时,界面张力达到0.024 mN/m。 Interfacial tension of kerosene-water system with different types of surfactant (anionic,cationic and nonionic surfactant as well as polymeric Gemini surfactant and asymmetric amphoteric Gemini surfactants) was investigated and compared.Results showed that nonionic surfactant is the one which may display lowest interfacial tension of 0.690 mN/m.Ethoxylated octylphenol nonionic surfactant (OP type) was selected to be blended with different types of other surfactants to examine the effects of type of the blend surfactant and their mass ratio,as well as the overall mass concentration on the interfacial tension of the mimetic oil-water system.Results showed the blend surfactant composed of ethoxylated octylphenol and asymmetric amphoteric Gemini surfactant (C15EC-S-C16,laboratory prepared) with mass ratio of 7∶3 and overall mass concentration of 50 g/L can reduce the interfacial tension to a minimum value of 0.024 mN/m. 参考文献 | 相关文章 | 计量指标

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柠檬酸酐的合成与表征 Synthesis and characterization of citric acid anhydride 金柱,张军,杨效益,杨秀全,周媛 2016 (4):  212-215.  doi: 10.13218/j.cnki.csdc.2016.04.007 摘要 ( 721 )   PDF(710KB) ( 556 )   以无水柠檬酸和乙酸酐为原料合成柠檬酸酐,通过单因素试验利用滴定法考察投料摩尔比、反应温度以及溶剂用量对反应转化率和收率的影响。结果表明:反应温度为52 ℃,n(乙酸酐)∶n(无水柠檬酸)=1.2∶1,n(乙酸)∶n(无水柠檬酸)=1.0∶1,反应时间为1.5 h时,柠檬酸酐收率达88.8%。利用红外光谱、核磁共振氢谱和质谱表征了合成产物,证明其为五元环状柠檬酸酐。 Citric acid anhydride was prepared in laboratory with anhydrous citric acid and acetic anhydride as starting materials.Effects of mole ratio of the reactants,reaction temperature and dosage of solvent on the conversion and the yield were investigated with titration method via single factor tests.Results indicated that the yield of citric acid anhydride is 88.8% at the suitable conditions as reaction temperature 52 ℃,reaction time 1.5 h,n(acetic anhydride)∶n(citric acid)=1.2 ∶1 and n(acetic acid)∶n(citric acid)=1.0∶1.Chemical structure of the product was characterized by FT-IR,1H NMR and MS,and the results of characterization showed that the product is a five member cyclo-anhydride. 参考文献 | 相关文章 | 计量指标

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大豆粕加压酸解工艺及其产物表面活性的研究 Study on the dissolution of soybean meal and the surface activity of the dissolved products 程海涛, 申献双 2016 (4):  216-218.  doi: 10.13218/j.cnki.csdc.2016.04.008 摘要 ( 273 )   PDF(637KB) ( 346 )   实验研究了加压酸解下大豆粕新溶解工艺,其较佳反应条件为:硫酸质量分数为20%,反应时间为20 min,温度(压强)为110 ℃(0.104 5 MPa),液料质量比为10。通过对大豆粕溶解液表面活性的测试可知其表面活性较好。 A new process for the acid dissolution of soybean meal under pressure was studied.The optimum conditions for the dissolution process were studied with solubility of soybean meal through orthogonal test.The results showed that the optimum dissolution conditions are:sulfuric acid mass fraction,20%;reaction time,20 min;temperature (pressure),110 ℃ (0.104 5 MPa);liquid to solid mass ratio,10.Surface activity test of the dissolved soybean meal showed that the product displays good surface activity. 参考文献 | 相关文章 | 计量指标

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海藻酸辛酰胺的制备及其协同氨基SiO2纳米粒稳定液体石蜡/水乳液的研究 Preparation of alginate caprylamide and its function for stabilizing liquid paraffin/water emulsions in cooperationwith amino-silica nanoparticles 陈秀琼,颜慧琼,冯玉红,史载锋,王向辉,林强 2016 (4):  219-225.  doi: 10.13218/j.cnki.csdc.2016.04.00 摘要 ( 234 )   PDF(6824KB) ( 272 )   以辛胺为疏水改性剂,采用酰化法制得具有两亲性的海藻酸辛酰胺(ACA)。将ACA与采用修正Stber法制备的氨基二氧化硅(SiO2-NH2)纳米粒混合,在超声的作用下制得O/W型Pickering乳液。通过FT-IR,1H NMR和荧光光谱对ACA的结构和性能进行表征。并采用激光粒度和Zeta电位分析仪、接触角测量仪和光学显微镜探究了ACA,SiO2-NH2及其协同水分散体系的胶体性能和相应的Pickering乳液的形貌。结果表明:ACA的取代度为0.29,在0.15 mol/L NaCl水溶液中的临界聚集浓度(cac)为0.42 g/L,表现出较强的两亲性能。ACA通过静电作用力成功地吸附于SiO2-NH2纳米粒上,使水动力学粒径只有155 nm的SiO2-NH2纳米粒增长至386 nm,Zeta电位由+22.2 mV转变为-30.7 mV,在水溶液中能够表现出良好的稳定性。吸附于SiO2-NH2纳米粒表面的ACA可以抑制无机纳米粒的聚沉,而游离的ACA形成的胶束结构的疏水内腔能够增溶油滴,减少小油滴的聚并。光学显微镜中出现了粒径较大的Pickering 乳液液滴和粒径较小的传统乳液液滴共存的现象,当ACA质量浓度在0.5 cac~1.0 cac时,2种乳液共存现象最为显著。 Amphiphilic alginate caprylamide (ACA) was prepared via the amidation using the octylamine as a hydrophobic modifier.Then,O/W Pickering emulsions were prepared by mixing ACA with SiO2-NH2 nanoparticles formed by modified Stber method under the action of ultrasonic wave.The structure and performance of ACA were characterized by FT-IR,1H NMR and fluorescence spectrum.The colloidal performance of ACA,SiO2-NH2 and their synergistic water dispersion system,as well as the morphology of the corresponding Pickering emulsions were investigated by the means of laser particle size and Zeta potential analyzer,contact angle meter and optical microscope.Experimental results showed that ACA with the degree of substitution of 0.29,exhibits good amphiphilic properties with the critical aggregation concentration (cac) of 0.42 g/L in 0.15 mol/L aqueous NaCl solution.ACA is successfully adsorbed on the surface of SiO2-NH2 nanoparticles via electrostatic force,causing the hydrodynamic size of SiO2-NH2 increases from 155 nm to 386 nm,and the Zeta potential of SiO2-NH2 changes from +22.2 mV to -30.7 mV,which can exhibit good stabilizing performance in aqueous solution.ACA absorbed on the surface of SiO2-NH2 nanoparticles can inhibit the aggregation and settlement of inorganic nanoparticles while the hydrophobic cavity of the micelle structure formed by free ACA can solubilize the oil droplets,reduce the coalescence of small oil droplets.The co-existence of larger Pickering emulsion droplets and smaller traditional emulsion droplets appear in the optical microscope images.When the mass concentration of ACA is in the range of 0.5 cac-1.0 cac,the co-existence of the two kinds of emulsions is the most obvious phenomenon. 参考文献 | 相关文章 | 计量指标

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灵芝发酵液的成分检测及美白与抗衰老功效评价 Analysis of fermentation liquor of Ganoderma lucidum and evaluation of its whitening and anti-senility efficacy 赵丹,许丹妮,王冬冬,张佳婵,李萌,王昌涛 2016 (4):  226-230.  doi: 10.13218/j.cnki.csdc.2016.04.010 摘要 ( 478 )   PDF(1649KB) ( 382 )   为开发灵芝发酵液在化妆品领域的应用,使用葡萄酒酵母发酵灵芝并测定发酵液中所含有的多糖、多酚、黄酮和多肽含量。通过DPPH自由基清除实验和羟自由基清除实验对灵芝发酵液的抗氧化能力进行检测,并测定其对成纤维细胞存活率的影响以评估其可能在抗衰老方面发挥的作用。最后通过体外酪氨酸酶实验和小鼠黑色素瘤细胞内的酪氨酸酶活性及黑色素合成抑制实验对灵芝发酵液的美白功效进行评价。结果表明,灵芝发酵液富含多糖,质量浓度为9.910 g/L,多酚、黄酮和多肽的质量浓度分别为0.054,0.045和2.931 g/L。体积分数分别为25.89%和42.18%的灵芝发酵液可清除50%的DPPH自由基和羟自由基;体积分数为0.05%~0.2%范围内的灵芝发酵液可有效促进成纤维细胞增殖;灵芝发酵液对酪氨酸酶活性抑制率高达73.22%,其通过抑制酪氨酸酶活性起到抑制黑色素合成的作用。因此灵芝发酵液具有一定的抗衰老和美白功效。 To develop the application of fermentation liquor of Ganoderma lucidum in the field of cosmetics,Saccharomyces ellipsoideus were used to acquire fermentation liquor Ganoderma lucidum,and the content of total polysaccharides,total polyphenols,total flavones and total polypeptides in the fermentation liquor were determined.The scavenging activity of OH·free radicals and DPPH free radicals as well as the influence on fibroblasts viability were measured to evaluate the possible anti-senility effect of the fermentation liquor.Finally,via in vitro tyrosinase activity test and intracellular tyrosinase activity test on melanin synthesis of mouses as well as melanin inhibition test,the evaluation for whitening effect of the fermentation liquor was conducted.Results showed that the fermentation liquor of Ganoderma lucidum contains 9.910 g/L of total polysaccharides,0.054 g/L of total polyphenols,0.045 g/L of total flavones,and 2.931 g/L of total polypeptides.The fermentation liquor with 25.89% and 42.18% volume fraction of fermentation liquor of Ganoderma lucidum could eliminate 50% OH·free radical and DPPH free radical.The fermentation liquor with 0.05%-0.2% volume fraction can promote fibroblasts proliferation effectively.The activity of tyrosinase is inhibited significantly by the fermentation liquor of Ganoderma lucidum and the inhibition rate reaches 73.22%.The fermentation liquor of Ganoderma lucidum could inhibit melanin synthesis by decreasing activity of tyrosinase.The fermentation liquor of Ganoderma lucidum exhibits efficacy for anti-senility and whitening. 参考文献 | 相关文章 | 计量指标

专论与综述

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三聚表面活性剂的研究进展 Research work development with respect to trimeric surfactants 廖学明,高志农,夏衍,卫婉英,周航,潘晨晨 2016 (4):  231-237.  doi: 10.13218/j.cnki.csdc.2016.04.011    摘要 ( 173 )   PDF(1222KB) ( 377 )   综述了三聚表面活性剂的分类、合成方法、结构对性能的影响以及应用。根据亲水头基的电性不同,三聚表面活性剂可分为阳离子型、阴离子型、非离子型和两性离子型4类。根据其结构特点,设计了不同亲水头基、不同中间连接基团和不同尾链的三聚表面活性剂的合成路线。最后介绍了三聚表面活性剂的性能及其在纳米材料的制备、乳液聚合等领域的应用,并对其未来的发展趋势进行了展望。 Classification and synthesis method of trimeric surfactans as well as effect of structure on their performance and applications were summarized.According to the different electrical property of hydrophilic head groups of trimeric surfactants,they can be classified into four classes,as cationic type,anionic type,nonionic type and amphoteric type.Based upon their structure characteristics,designs of various synthesis routes,for preparing trimeric surfactants with different head groups,different space groups and different tail chains were described.Finally,performance of trimeric surfactants and their applications in various domains,such as preparation of nanomaterials,emulsion polymerization and so on were introduced.The future trend of development in this field was predicted as well. 参考文献 | 相关文章 | 计量指标

分析与检测

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高效液相色谱法检测防晒类化妆品中的尿刊酸及其乙酯 Determination of urocanic acid and its ethyl ester in sunscreen cosmetics by HPLC 郭项雨,马强,孟宪双,李焘,李文雅,白桦 2016 (4):  238-242.  doi: 10.13218/j.cnki.csdc.2016.04.012 摘要 ( 259 )   PDF(777KB) ( 344 )   研究建立了同时测定防晒类化妆品中尿刊酸及其乙酯的高效液相色谱检测方法及质谱确证方法。化妆品样品以甲醇为提取溶剂进行超声提取,提取液经离心处理、微孔滤膜过滤后测定。采用XTerra MS C18色谱柱(4.6 mm×250 mm,5 μm)进行分离,以甲醇-5 mmol/L四丁基溴化铵溶液(体积比为30∶70)为流动相进行等梯度洗脱,流速为1.0 mL/min,柱温为35 ℃,检测波长为285 nm,外标法定量。防晒类化妆品中尿刊酸及其乙酯的方法定量限均为5 mg/kg,在低、中、高3个添加水平范围内平均回收率为80.1%~103.8%,相对标准偏差(RSD)为1.2%~6.9%。对于疑似阳性的样品,进一步采用液相色谱-串联质谱法进行确证分析。该方法准确、快速、灵敏度高,适用于防晒类化妆品的实际检验工作。 A high performance liquid chromatography (HPLC) was established for the simultaneous determination of urocanic acid and its ethyl ester in sunscreen cosmetics.The result was comfirmed with mass spectrometry.Cosmetic samples were extracted with methanol under assistance of ultrasonic wave and the extract was centrifuged and filtered with a microporous membrane filter.Then the filtrate was transfer for HPLC analysis using an XTerra MS C18 column (4.6 mm×250 mm,5 μm).The mobile phase was a solution composed of methanol and 5 mmol/L tetrabutylammonium bromide (30∶70) with isocratic elution.The column temperature was set at 35 ℃.The flow rate was 1 mL/min and the wavelength of detection was at 285 nm.The quantification was carried out by external standard method.The experimental results indicated that the limits of quantification (LOQs) for urocanic acid and its ethyl ester were both 5 mg/kg.The mean recoveries at three spiked levels ranged from 80.1% to 103.8% with the relative standard deviations (RSD) between 1.2% and 6.9%.The suspected positive samples were subjected to further verification by LC-MS/MS.The method is accurate,rapid,sensitive,and can be used for the inspection of sunscreen cosmetics. 参考文献 | 相关文章 | 计量指标