表面活性剂与蛋白质在水体系中的相互作用机制及应用

doi:10.3969/j.issn.2097-2806.2025.09.014

摘要/Abstract

摘要：

表面活性剂与蛋白质相互作用的机制研究对于促进其应用领域的发展具有重要意义。本文通过分析表面活性剂与蛋白质在体相以及界面处的复杂行为，重点探讨了其静电作用、疏水作用、界面竞争吸附机制以及调控体系参数对作用机制的显著影响。并将两者相互作用与实际应用充分衔接，阐述了表面活性剂与蛋白质相互作用在医药领域、食品工业及日用化学品领域的具体应用，总结了表面活性剂-蛋白质体系中各因素发生变化时表现出的特定分子行为与其应用间的联系。旨在为新型高效表面活性剂的开发及与之相关的蛋白质功能的精准调控提供理论依据。

关键词: 表面活性剂, 蛋白质, 相互作用机制, 应用

Abstract:

The research of the interaction mechanism between surfactants and proteins is of great significance for promoting the development of their applications across various fields. This review has focused on analyzing the behaviors of mixtures of surfactants and proteins both in bulk phase and at interfaces, with emphasis on the mechanisms involving electrostatic interactions, hydrophobic interactions, and competitive adsorption at interfaces, as well as the significant impact of regulating system parameters on these mechanisms. Furthermore, this review has combined surfactant-protein interactions with practical applications, elaborating on their specific roles in pharmaceutical industry, food industry, and daily chemical products. The specific molecular behaviors of surfactant-protein systems with varying factors and their relationships to applications were also summarized. This review might provide theoretical basis for the development of novel, efficient surfactants and for the regulation of related protein functionalities.

Key words: surfactant, protein, interaction mechanism, application

中图分类号:

TQ423

刘娱彤, 苑冰冰, 韩甜甜, 陈功, 慕永航, 宋林花, 王子. 表面活性剂与蛋白质在水体系中的相互作用机制及应用[J]. 日用化学工业（中英文）, 2025, 55(9): 1198-1206.

Yutong Liu, Bingbing Yuan, Tiantian Han, Gong Chen, Yonghang Mu, Linhua Song, Zi Wang. Interaction mechanism and application of the aqueous mixtures of surfactants and proteins[J]. China Surfactant Detergent & Cosmetics, 2025, 55(9): 1198-1206.

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