Abstract: Through the separate antimicrobial efficacy evaluation of 1,2-hexanediol and p-hydroxyacetophenone,a new synergistic blend of 1,2-hexanediol and p-hydroxyacetophenone was proposed.Inhibiting effect for bacteria and fungi of the blend system with separate blending ratios in various cosmetic formulations,including lotions,O/W emulsions,gels and creams et al.were examined.Results showed that when mass fraction of both 1,2-hexanediol and p-hydroxyacetophenone are 0.5%,or mass fraction of 1,2-hexanediol and p-hydroxyacetophenone is 0.8% and 0.4% respectively,excellent inhibiting effect for bacteria and fungi in all above-mentioned cosmetic products can be obtained.

Key words: cosmetics, preservation, 1,2-hexanediol, p-hydroxyacetophenone, blending