China Surfactant Detergent & Cosmetics ›› 2024, Vol. 54 ›› Issue (3): 353-359.doi: 10.3969/j.issn.2097-2806.2024.03.015
• Analytical methods and testing • Previous Articles Next Articles
Liyuan Zhang,Linqi Yan*(),Qiaoyuan Cheng,Lvye Qi,Rong Wang,Liuqian Huang
Received:
2023-03-10
Revised:
2024-02-28
Online:
2024-03-22
Published:
2024-03-25
Contact:
*Tel.:+86-18058705215, E-mail: CLC Number:
Liyuan Zhang, Linqi Yan, Qiaoyuan Cheng, Lvye Qi, Rong Wang, Liuqian Huang. Determination of 14 kinds of α-hydroxy acids and hydroxy esters in cosmetics[J].China Surfactant Detergent & Cosmetics, 2024, 54(3): 353-359.
Tab. 1
Mass spectrum parameters of 14 compounds"
序号 | 组分名称 | 母离子(m/z) | 子离子(m/z) | 碰撞能/V |
---|---|---|---|---|
1 | 葡糖醛酸 | 193.2 | 113.1 | -14 |
131.1 | -11 | |||
2 | 酒石酸 | 149.1 | 87.1 | -14 |
73 | -18 | |||
3 | 羟基乙酸 | 75.2 | 45.1 | -16 |
47.1 | -15 | |||
4 | 苹果酸 | 133.2 | 115 | -16 |
71.2 | -17 | |||
5 | 乳酸 | 89.2 | 43.1 | -13 |
45.1 | -15 | |||
6 | 柠檬酸 | 191.1 | 111.1 | -12 |
87.1 | -11 | |||
7 | 2-羟基丁酸 | 103.2 | 57.1 | -13 |
45.1 | -16 | |||
8 | 乳酸甲酯 | 104.9 | 45 | +9 |
33 | +15 | |||
9 | 扁桃酸 | 151.2 | 107.1 | -7 |
10 | 乳酸乙酯 | 118.9 | 91.1 | +9 |
45 | +17 | |||
47.1 | +11 | |||
11 | 乳酸丁酯 | 147.3 | 45.1 | +14 |
91.1 | +7 | |||
63 | +8 | |||
12 | 二苯乙醇酸 | 227.1 | 183.3 | -9 |
13 | 柠檬酸三乙酯 | 299.2 | 210.7 | +13 |
178.7 | +15 | |||
14 | 羟基辛酸 | 159.2 | 113.2 | -16 |
45 | -17 |
Tab. 2
Linear range, regression equations, correlation coefficients, limits of detection and quantitation for 14 compounds"
组分 | 线性范围/(μg/mL) | 回归方程 | R2 | 检出限/(μg/g) | 定量限/(μg/g) |
---|---|---|---|---|---|
葡糖醛酸 | 98.16~3 926 | Y=0.151 7X-1.394 9 | 0.999 7 | 160 | 480 |
酒石酸 | 52.04~2 082 | Y=0.656 3X+3.346 0 | 0.999 9 | 60 | 180 |
羟基乙酸 | 97.34~3 894 | Y=0.196 3X-0.492 3 | 1 | 40 | 120 |
苹果酸 | 101.1~4 045 | Y=0.341 6X-1.924 4 | 1 | 40 | 120 |
乳酸 | 123.6~4 942 | Y=0.223 1X-3.759 0 | 1 | 100 | 300 |
柠檬酸 | 124.7~4 989 | Y=0.329 2X-3.367 4 | 1 | 40 | 120 |
2-羟基丁酸 | 120.7~4 829 | Y=0.173 2X-2.353 9 | 1 | 80 | 240 |
乳酸甲酯 | 122.1~4 885 | Y=0.183 3X-0.167 7 | 1 | 80 | 240 |
扁桃酸 | 2.893~115.7 | Y=9.793 5X+2.355 8 | 1 | 2 | 6 |
乳酸乙酯 | 100.3~4 013 | Y=0.178 7X+0.883 2 | 1 | 80 | 240 |
乳酸丁酯 | 121.0~4 013 | Y=0.182 8X-0.159 3 | 1 | 80 | 240 |
二苯乙醇酸 | 2.867~114.7 | Y=17.024 1X-2.274 8 | 1 | 2 | 6 |
柠檬酸三乙酯 | 123.8~4 950 | Y=17.024 1X-2.274 8 | 1 | 80 | 240 |
羟基辛酸 | 123.8~4 951 | Y=0.146 4X+5.551 0 | 1 | 40 | 120 |
Tab. 3
The recovery rate and RSD of 14 compounds"
组分 | 低浓度回收率/% | RSD/% | 高浓度回收率/% | RSD/% | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
水 | 乳 | 凝胶 | 膏霜 | 水 | 乳 | 凝胶 | 膏霜 | 水 | 乳 | 凝胶 | 膏霜 | 水 | 乳 | 凝胶 | 膏霜 | ||||
葡糖醛酸 | 113.3 | 107 | 103.7 | 95.8 | 2.7 | 1.7 | 0.8 | 0.6 | 99.2 | 102.9 | 101.1 | 91.6 | 0.4 | 0.4 | 0.7 | 0.8 | |||
酒石酸 | 94.7 | 98.7 | 97.1 | 90.4 | 0.5 | 0.9 | 1.8 | 1.5 | 100.3 | 101.5 | 100.8 | 106.2 | 0.3 | 0.6 | 0.8 | 0.7 | |||
羟基乙酸 | 93.4 | 103.2 | 96.4 | 97.1 | 0.8 | 0.5 | 1.8 | 2.1 | 98.5 | 102.5 | 100.2 | 101.9 | 0.4 | 0.6 | 0.8 | 0.5 | |||
苹果酸 | 102.1 | 106.1 | 104.6 | 102 | 0.2 | 0.6 | 0.7 | 1.7 | 98.2 | 101.6 | 100.3 | 102.6 | 0.6 | 0.7 | 0.7 | 0.6 | |||
乳酸 | 105.5 | 109.8 | 106.7 | 104.1 | 0.2 | 0.8 | 0.5 | 0.9 | 100.7 | 107.6 | 103.2 | 104.1 | 0.3 | 0.7 | 0.8 | 0.7 | |||
柠檬酸 | 104.2 | 107.3 | 106 | 103 | 0.3 | 0.4 | 0.8 | 1 | 99 | 101.5 | 100.4 | 102.4 | 0.4 | 0.6 | 0.8 | 0.6 | |||
2-羟基丁酸钠 | 105.4 | 107.1 | 96.9 | 103.1 | 3.1 | 0.7 | 0.8 | 0.8 | 98.7 | 101 | 98.2 | 102.3 | 0.7 | 0.7 | 0.9 | 0.5 | |||
乳酸甲酯 | 104.3 | 105.6 | 105.5 | 100.6 | 0.5 | 0.6 | 0.7 | 1 | 100.8 | 99.5 | 101 | 101.1 | 0.6 | 0.4 | 0.9 | 0.5 | |||
扁桃酸 | 106.1 | 109.2 | 107.3 | 95.6 | 0.8 | 0.6 | 1 | 1.1 | 99.3 | 102.1 | 99.3 | 101.4 | 0.6 | 0.7 | 1 | 0.5 | |||
乳酸乙酯 | 110.9 | 111.9 | 115.4 | 107.1 | 1.7 | 1.8 | 0.9 | 3.6 | 102 | 101 | 102.9 | 101.5 | 0.6 | 0.4 | 0.6 | 0.6 | |||
乳酸丁酯 | 109.9 | 112.8 | 112.9 | 104.8 | 0.6 | 0.6 | 0.9 | 2.4 | 103.5 | 100.2 | 102.9 | 98.3 | 0.5 | 0.7 | 0.6 | 0.9 | |||
二苯乙醇酸 | 87.8 | 98.2 | 98.3 | 97.7 | 1.9 | 1.8 | 3.2 | 1.9 | 97.4 | 88.4 | 91.8 | 87.7 | 0.3 | 2.3 | 2.2 | 2.1 | |||
柠檬酸三乙酯 | 100.5 | 109.3 | 103.4 | 103 | 0.4 | 2.8 | 1.4 | 0.7 | 99.1 | 102.2 | 99.7 | 99.4 | 0.4 | 0.9 | 0.9 | 0.6 | |||
羟基辛酸 | 99.5 | 101.5 | 100.7 | 99.3 | 4 | 0.5 | 3.8 | 1.3 | 98.6 | 91.4 | 96.8 | 92.5 | 0.4 | 1.4 | 1.2 | 1 |
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