神经调节在敏感肌肤中的作用

doi:10.3969/j.issn.2097-2806.2026.03.013

Abstract

Abstract:

The role of neuromodulation in skin health and disease is increasingly recognized, as it is closely related to skin sensitivity, barrier function, aging, and pigmentation. This review aims to explore the critical role of neuromodulation in sensitive skin, analyzing its impact from three perspectives: neurovascular reactivity, sensory characteristics, and emotional skincare. Additionally, it proposes recommendations for future research directions.

Key words: sensitive skin, neurotransmitters, emotional skincare, neurovascular reactivity, sensory receptors

CLC Number:

TQ658

Dongping Qi,Fengtong Shen,Junliang Zhang,Sicong Liu,Yue Wu. The role of neuromodulation in sensitive skin[J].China Surfactant Detergent & Cosmetics, 2026, 56(3): 376-385.

Figures/Tables 6

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References 59

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刺激类型	温度/机制	激活受体
热刺激	>42 ℃	TRPV1
	>53 ℃	TRPV2
	25~33 ℃	TRPV3/TRPV4
冷刺激	<15 ℃	TRPM8（<10~15 ℃）、TRPA1（<17 ℃）
机械刺激	牵张、压缩、剪切力等	TRPV4、ASIC、Piezo1/Piezo2
化学刺激	1）微生物；2）炎症介质：前列腺（PGE2、PGI2）、神经营养因（NGF）、神经肽（SP、CGRP）；3）非炎症介质：GABA、阿片肽、大麻素	TRP家族（如TRPV1、TRPA1）、TOLL受体

The role of neuromodulation in sensitive skin

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