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日用化学工业（中英文）

日用化学工业 ›› 2017, Vol. 47 ›› Issue (1): 28-31.doi: 10.13218/j.cnki.csdc.2017.01.006

• 开发与应用 • 上一篇    下一篇

小球藻类金属硫蛋白抗紫外辐射的作用研究

杨红1,2, 黄晓淳1,3, 黄婧筠1, 彭爱红1, 黄志勇1   

  1. 1.集美大学 食品与生物工程学院,福建 厦门 361021;
    2.龙岩学院 科研处,福建 龙岩 364012;
    3.厦门华厦学院 健康管理系,福建 厦门 361021
  • 收稿日期:2016-08-10 发布日期:2019-03-19
  • 通讯作者: 黄志勇,教授,博士,电话:13459225886,E-mail:zhyhuang@jmu.edu.cn。
  • 作者简介:杨 红,女,福建人,硕士,电话:18259226562,E-mail:354341151@qq.com。
  • 基金资助:
    厦门市海洋经济发展专项(14GZP67NF31);集美大学创新团队基金资助项目(2010A007)

Protective effect of Zn-MT-like extracted from C.vulgaris for NIH/3T3 cells against ultraviolet irradiation

YANG Hong1,2, HUANG Xiao-chun1,3, HUANG Jing-yun1, PENG Ai-hong1, HUNG Zhi-yong1   

  1. 1.College of Food and Biological Engineering,Jimei University,Xiamen,Fujian 361021,China;
    2.Management Office of Scientific Research,Longyan University,Longyan,Fujian 364012,China;
    3.Department of Health Management,Xiamen Huaxia University,Xiamen,Fujian 361021,China
  • Received:2016-08-10 Published:2019-03-19

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摘要： 建立了小鼠胚胎成纤维(NIH/3T3)细胞紫外辐射损伤的实验模型,考察小球藻类金属硫蛋白(Zn-MT-like)对NIH/3T3细胞紫外辐射的保护作用。结果表明,小球藻Zn-MT-like对NIH/3T3细胞的生长无抑制作用,且具有较强的抗紫外辐射能力。质量浓度为10 g/L的小球藻Zn-MT-like可显著减少NIH/3T3细胞空泡、降低细胞裂解的程度,可使经紫外辐射的NIH/3T3细胞保持较好的活性。

关键词: 抗紫外辐射, 小球藻, 类金属硫蛋白, NIH/3T3细胞模型

Abstract: A laboratory model for testing ultraviolet irradiation damage of fibroblast (NIH/3T3) of mouse embryo was established;and it was applied for examination of protective effect of Zine-binding metallothionein-like (Zn-MT-like) extracted from C.vulgaris for NIH/3T3 cells against ultraviolet irradiation.Results showed that the Zn-MT-like presents a strong protective effect for the NH/3T3 cells from irradiation damage.For example,the Zn-MT-like at mass concentration of 10 g/L can effectively reduce the NIH/3T3 cell cavity and cell fragmentation under the ultraviolet irradiation,and maintaining rather good cell activity.

Key words: anti ultraviolet irradiation, C.vulgaris, Zn-MT-like, NIH/3T3 cells model

中图分类号: 

  • Q946