荧光纳米材料的研究进展

doi:10.3969/j.issn.2097-2806.2023.05.009

摘要/Abstract

摘要：

荧光纳米粒子（NPs）是过去十年研究和开发的主要焦点。与传统的荧光有机染料相比，荧光纳米颗粒具有独特的化学和光学特性，如更亮的荧光、更高的光稳定性和更高的生物相容性。此外，纳米颗粒还可以作为实现超分子组装的多价支架，因为它们的高表面体积比允许不同的空间域被功能化，这可以为实现不同的传感方案提供一个多功能的合成平台。本文综述了包括半导体NPs（量子点）、金属NPs、二氧化硅NPs等荧光纳米粒子近年来的研究进展，典型的例子展示了荧光纳米材料，包括半导体纳米晶体，金属纳米颗粒，硅基纳米材料是如何制造的。本文还讨论了荧光NPs在市场地位相关的挑战。

关键词: 荧光纳米粒子, 半导体NPs（量子点）, 金属NPs, 二氧化硅NPs

Abstract:

Fluorescent nanoparticles have been the focus of research and development in the past decade. Compared with traditional fluorescent organic dyes, fluorescent nanoparticles have unique chemical and optical properties, such as brighter fluorescence, higher light stability, and higher biocompatibility. In addition, nanoparticles （NPs） can also be used as multivalent scaffolds for supramolecular assembly, because their high surface-area-to-volume ratio allows different domains to be functionalized, which can provide a multifunctional synthesis platform for different sensing schemes. This paper reviews the research progress of fluorescent nanoparticles including semiconductor NPs （quantum dots）, metal NPs and silica NPs in recent years. Typical examples show how fluorescent nanomaterials, including semiconductor nanocrystals, metal nanoparticles and silicon-based nanomaterials, are manufactured. The challenges related to the market position of fluorescent NPs are also discussed.

Key words: fluorescent nanoparticles, semiconductor NPs （quantum dots）, metal NPs, silica NPs

中图分类号:

TB383.1

李曦, Saule Aidarova, 殷夏, Miras Issakhov, 徐德荣, 康万利. 荧光纳米材料的研究进展[J]. 日用化学工业（中英文）, 2023, 53(5): 551-559.

Li Xi, Aidarova Saule, Yin Xia, Issakhov Miras, Xu Derong, Kang Wanli. Research progress of fluorescent nanomaterials[J]. China Surfactant Detergent & Cosmetics, 2023, 53(5): 551-559.

图/表 12

参考文献 33

[1]	Bruchez M, Moronne M, Gin P, et al. Semiconductor nanocrystals as fluorescent biological labels[J]. Science, 1998, 281(5385): 2013-2016. pmid: 9748157
[2]	Derfus A M, Chan W C, Bhatia S N. Probing the cytotoxicity of semiconductor quantum dots[J]. Nano Letters, 2004, 4(1): 11-18. doi: 10.1021/nl0347334 pmid: 28890669
[3]	Czarnik A W. Chemical communication in water using fluorescent chemo sensors[J]. Accounts of Chemical Research, 1994, 27(10): 302-308. doi: 10.1021/ar00046a003
[4]	Bright F V. Bioanalytical applications of fluorescence spectroscopy[J]. Analytical Chemistry, 1988, 60: 1031-1039. pmid: 3067623
[5]	Duan Chengchen, Liang Liuen, Li Li, et al. Recent progress in upconversion luminescence nanomaterials for biomedical applications[J]. Journal of Materials Chemistry B, 2018, 6(2): 192-209. doi: 10.1039/c7tb02527k pmid: 32254163
[6]	Wehrenberg B L, Wang Congjun, Guyot-Sionnest P. Interband and intraband optical studies of PbSe colloidal quantum dots[J]. The Journal of Physical Chemistry B, 2002, 106(41): 10634-10640. doi: 10.1021/jp021187e
[7]	Alivisatos A P. Semiconductor clusters, nanocrystals, and quantum Dots[J]. Science, 1996, 271(5251): 933-937. doi: 10.1126/science.271.5251.933
[8]	Currie M J, Mapel J K, Heidel T D, et al. High-efficiency organic solar concentrators for photovoltaics[J]. Science, 2008, 321(5886): 226-228. doi: 10.1126/science.1158342 pmid: 18621664
[9]	Peng Z A, Peng Xiaogang. Formation of high-quality CdTe, CdSe, and CdS nanocrystals using CdO as precursor[J]. Journal of the American Chemical Society, 2001, 123(1): 183-184. pmid: 11273619
[10]	Brumer M, Kigel A, Amirav L, et al. PbSe/PbS and PbSe/PbSe_xS_1-_x core/shell nanocrystals[J]. Advanced Functional Materials, 2005, 15(7): 1111-1116. doi: 10.1002/(ISSN)1616-3028
[11]	Lifshitz E, Brumer M, Kigel A, et al. Air-stable PbSe/PbS and PbSe/PbSe_xS_1-_x core-shell nanocrystal quantum dots and their applications[J]. The Journal of Physical Chemistry B, 2006, 110(50): 25356-25365. doi: 10.1021/jp0644356
[12]	Cao Li, Meziani M J, Sahu S, et al. Photoluminescence properties of graphene versus other carbon nanomaterials[J]. Acs Nano, 2016, 10(1): 484-491. doi: 10.1021/acsnano.5b05406
[13]	Khandare J, Satavalekar J, Bhansali S. PEG-conjugated highly dispersive multifunctional magnetic multi-walled carbon nanotubes for cellular imaging[J]. Nanoscale, 2012, 4(3): 837-844. doi: 10.1039/c1nr11540e pmid: 22170574
[14]	Liang Xiao. Study on structure and properties of nanomaterials based on fluorescent quantum dots[D]. Wuhan: Wuhan University of Technology, 2019.
[15]	Dong Yongqiang, Wang Qian, Wan Lisi, et al. Carbon based dot capped silver nanoparticles for efficient surface-enhanced Raman scattering[J]. Journal of Materials Chemistry C, 2016, 4(31): 7472-7477. doi: 10.1039/C6TC01943A
[16]	Liu Hongwei. Preparation fluorescence imaging and antibacterial application of multifunctional carbon quantum dot-silver nanocomposites[D]. Taiyuan: Taiyuan University of Technology, 2020.
[17]	Faraday M. The Bakerian lecture: experimental relations of gold (and other metals) to light[J]. Philosophical Transactions of the Royal Society of London, 1857, 147: 145-181. doi: 10.1098/rstl.1857.0011
[18]	Turkevich J, Stevenson P C, Hillier J. A study of the nucleation and growth processes in the synthesis of colloidal gold[J]. Discussions of the Faraday Society, 1951, 11: 55-75. doi: 10.1039/df9511100055
[19]	Kim Y R, Mahajan R K, Kim J S, et al. Highly sensitive gold nanoparticle-based colorimetric sensing of mercury (Ⅱ) through simple ligand exchange reaction in aqueous media[J]. ACS Applied Materials and Interfaces, 2010, 2(1): 292-295. doi: 10.1021/am9006963
[20]	Duan Junling, Yin Hongzong, Wei Ranran, et al. Facile colorimetric detection of Hg²⁺ based on anti-aggregation of silver nanoparticles[J]. Biosensors and Bioelectronics, 2014, 57: 139-142. doi: 10.1016/j.bios.2014.02.007 pmid: 24583318
[21]	Petty J T, Zheng Jie, Hud N V, et al. DNA-templated Ag nanocluster formation[J]. Journal of the American Chemical Society, 2004, 126(16): 5207-5212. doi: 10.1021/ja031931o pmid: 15099104
[22]	Tanaka K, Yamada Y, Shionoya M. Formation of silver(Ⅰ) -mediated DNA duplex and triplex through an alternative base pair of pyridine nucleobases[J]. Journal of the American Chemical Society, 2002, 124(30): 8802-8803. doi: 10.1021/ja020510o
[23]	Li Tao, Zhang LiBing, Wang Erkang, et al. Ion-tuned DNA/Ag fluorescent nanoclusters as versatile logic device[J]. ACS Nano, 2011, 5(8): 6334-6338. doi: 10.1021/nn201407h pmid: 21732637
[24]	Yang Wen, Tian Jianniao, Ma Yefei, et al. A label-free fluorescent probe based on DNA-templated silver nanoclusters and exonuclease Ⅲ-assisted recycling amplification detection of nucleic acid[J]. Analytica Chimica Acta, 2015, 900: 90-96. doi: 10.1016/j.aca.2015.10.015 pmid: 26572843
[25]	Beltramello M, Gatos M, Mancin F, et al. A new selective fluorescence chemo sensor for Cu (Ⅱ) in water[J]. Tetrahedron Letters, 2001, 42(52): 9143-9146. doi: 10.1016/S0040-4039(01)01965-7
[26]	Bertazza L, Celotti L, Fabbrini G, et al. Cell penetrating silica nanoparticles doped with two-photon absorbing fluorophores[J]. Tetrahedron, 2006, 62(44): 10434-10440. doi: 10.1016/j.tet.2006.08.044
[27]	Gu Yao, Meng Guowen, Wang Meiling, et al. Co-functionalized Fe₃O₄@SiO₂ nanoparticles for fluorescence detection of trace Hg²⁺ and Zn²⁺ in aqueous solution[J]. Science China Materials, 2015, 58(7): 550-558. doi: 10.1007/s40843-015-0071-0
[28]	Li Zongxi, Barnes J C, Bosoy A, et al. Mesoporous silica nanoparticles in biomedical applications[J]. Chem. Soc. Rev., 2012, 41(7): 2590-2605. doi: 10.1039/c1cs15246g pmid: 22216418
[29]	Na H B, Lee J H, An K, et al. Development of a T1 contrast agent for magnetic resonance imaging using MnO nanoparticles[J]. Angew Chem., 2007, 119(28): 5493-5497. doi: 10.1002/(ISSN)1521-3757
[30]	Deffieux T, Younan Y, Wattiez N, et al. Low-intensity focused ultrasound modulates monkey visuomotor behavior[J]. Curr. Biol., 2013, 56(23): 2430-2433.
[31]	Huang P, Chen Y, Lin H, et al. Molecularly organic/inorganic hybrid hollow mesoporous organosilica nanocapsules with tumor-specific biodegradability and enhanced chemotherapeutic functionality[J]. Biomaterials, 2017, 125: 23-37. doi: S0142-9612(17)30091-1 pmid: 28226244
[32]	Xie Can. Preparation of functional nanomaterials and their Fluorescence imaging in vivo[D]. Changsha: Hunan University, 2011.
[33]	Feng Yi. Study on synergistic antitumor effect of tumor microenvironment responsive mesoporous silicon nanodrugs[D]. Chengdu: University of Electronic Science and Technology, 2022.