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日用化学工业 ›› 2019, Vol. 49 ›› Issue (5): 335-340.doi: 10.3969/j.issn.1001-1803.2019.05.010

• 专论与综述 • 上一篇    下一篇

敏感肌肤和微生态屏障

赵小敏,瞿欣   

  1. 亚什兰(中国)投资有限公司 上海创新研发中心,上海 200233
  • 收稿日期:2018-07-30 修回日期:2019-05-10 出版日期:2019-05-22 发布日期:2019-05-24
  • 作者简介:赵小敏(1980-),女,山西人,硕士,电话:13564329490,E-mail:rzhao@ashland.com。

Sensitive skin and skin microbiome

ZHAO Xiao-min,QU Xin   

  1. Shanghai Innovation Research Center, Ashland(China)Inc., Shanghai 200233, China
  • Received:2018-07-30 Revised:2019-05-10 Online:2019-05-22 Published:2019-05-24

摘要:

概览了国内外关于皮肤微生态屏障及其和敏感肌肤的关系,包括微生物在皮肤上的分布,微生物和皮肤的相互关系,敏感皮肤微生态屏障的重要性。论述了角质细胞如何特异性的识别共生菌群,共生菌群通过什么样的机制维护皮肤健康,以及微生态屏障失衡在多种类型敏感皮肤发病中的重要作用。同时提出了从护肤品角度出发,如何调控微生态屏障从而解决敏感肌肤问题。

关键词: 敏感皮肤, 微生态屏障, 模式识别受体, 抗菌多肽

Abstract:

This article reviews the recent study and development of skin microbiota and its relationship with sensitive skin. The distribution of the microbes on skin and their interaction with skin, and the impact of skin microbiome barrier on sensitive skin are reviewed and discussed. This content covers how keratinocyte specifically recognize commensal microbes, how they protect skin as immunity barrier and how the disrupted skin ecosystem influences different kinds of sensitive skin. The solution for sensitive skin is also reviewed and discussed based on optimizing skin ecosystems.

Key words: sensitive skin, skin microbiota, pattern recognition receptor(PRR), antimicrobial peptides(AMPs)

中图分类号: 

  • TQ658