山茱萸多糖手工皂的工艺研究及安全性评价

doi:10.3969/j.issn.1001-1803.2019.04.009

日用化学工业 ›› 2019, Vol. 49 ›› Issue (4): 248-252.doi: 10.3969/j.issn.1001-1803.2019.04.009

山茱萸多糖手工皂的工艺研究及安全性评价

刘芳,张茜,杨彬,何华康,杨磊,郭春花()

长治医学院,山西长治 046000

收稿日期:2018-07-23 修回日期:2019-03-29 出版日期:2019-04-22 发布日期:2019-04-24
通讯作者: 郭春花
作者简介:刘芳（1977-）,女,山西长治人,副教授,硕士,电话：（0355）3151521,E-mail：liufang@czmc.edu.cn。
基金资助:
山西省高等学校大学生创新创业训练计划项目2017302;长治医学院科研启动基金项目(QDZ201623)

Study on preparation process and safety evaluation of handmade soap containing Corni Fructus polysaccharide

LIU Fang,ZHANG Qian,YANG Bin,HE Hua-kang,YANG Lei,GUO Chun-hua()

Changzhi Medical College, Changzhi, Shanxi 046000, China

Received:2018-07-23 Revised:2019-03-29 Online:2019-04-22 Published:2019-04-24
Contact: Chun-hua GUO

摘要/Abstract

摘要：

采用冷制法,以橄榄油、椰子油、棕榈油、蜜蜡等天然植物油为皂基,以山茱萸多糖为抗菌有效成分,制备了山茱萸多糖手工皂,并对其进行了性能检测、抑菌效果及安全性评价。得到椰子油、棕榈油、橄榄油、蜜蜡的较佳质量分数分别为25%,25%,45%和5%,添加1%山茱萸多糖为较佳处方。总游离碱、游离苛性碱、水分和挥发物含量均符合QB/T 2485—2008《香皂》标准,皮肤刺激实验、急性眼刺激实验无明显刺激作用。结果表明山茱萸多糖手工皂安全、无刺激性,为山茱萸植物资源的综合利用提供了科学依据。

关键词: 手工皂, 山茱萸多糖, 工艺研究, 安全性评价

Abstract:

The handmade soap was prepared with the cold process using olive oil, coconut oil, palm oil and beeswax as soap base and polysaccharide of Corni Fructus as the functional component. The properties, antibacterial activity and safety of the soap were evaluated. The optimized proportions of coconut oil, palm oil, olive oil and beeswax were 25%, 25%, 45% and 5%, together with that of Corni Fructus polysaccharide being 1%. The indexes such as the total free base, free caustic alkali, water content and volatile oil were all consistent with the Chinese standards, and it was not irritant to the skin or eyes of rabbits. The results show that such handmade soap containing Corni Fructus polysaccharide is safe and nonirritating, which provides a scientific basis for utilization of the Corni Fructus.

Key words: handmade soap, polysaccharide of Corni Fructus, preparation process, safety evaluation

中图分类号:

TQ648

刘芳,张茜,杨彬,何华康,杨磊,郭春花. 山茱萸多糖手工皂的工艺研究及安全性评价[J]. 日用化学工业, 2019, 49(4): 248-252.

LIU Fang,ZHANG Qian,YANG Bin,HE Hua-kang,YANG Lei,GUO Chun-hua. Study on preparation process and safety evaluation of handmade soap containing Corni Fructus polysaccharide[J]. China Surfactant Detergent & Cosmetics, 2019, 49(4): 248-252.

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参考文献 17

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类别	w（测定值）/%				国家标准/%
类别	未加多糖	多糖1%	多糖2%	多糖4%	国家标准/%
总游离碱	0.167	0.201	0.193	0.184	≤0.3
游离苛性碱	0.069	0.070	0.072	0.070	≤0.1
水分和挥发物	1.666	2.020	2.269	3.701	≤30

组别	滴入1 h后			滴入24 h后			滴入48 h后			滴入72 h后
组别	结膜	巩膜	角膜	结膜	巩膜	角膜	结膜	巩膜	角膜	结膜	巩膜	角膜
对照组	0	0	0	0	0	0	0	0	0	0	0	0
未加多糖	0	0.5	0	0	0	0	0	0	0	0	0	0
1%多糖	0	0.5	0	0	0	0	0	0	0	0	0	0
2%多糖	0	0.7	0	0	0.5	0	0	0	0	0	0	0
4%多糖	0	0.5	0	0	0.2	0	0	0	0	0	0	0

山茱萸多糖手工皂的工艺研究及安全性评价

Study on preparation process and safety evaluation of handmade soap containing Corni Fructus polysaccharide

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处方	w/%
处方	椰子油	棕榈油	橄榄油	蜜蜡
1	20	20	55	5
2	25	25	45	5
3	30	30	35	5

处方	总分/分
处方	泡沫细致度	泡沫持久度	泡沫浓密度	滋润度	清洁力
1	22	22	20	21	21
2	23	22	22	21	23
3	22	21	15	14	15

w（多糖）/ %	总分/分
w（多糖）/ %	泡沫细致度	泡沫持久度	泡沫浓密度	滋润度	清洁力
0	23	22	22	21	23
1	27	25	24	23	21
2	22	23	20	20	22
4	20	20	14	14	15

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