掺羟基磷灰石牙膏对早期龋的修复及吸附镉离子作用研究

doi:10.13218/j.cnki.csdc.2014.05.059

日用化学工业 ›› 2014, Vol. 44 ›› Issue (5): 266-269.doi: 10.13218/j.cnki.csdc.2014.05.059

掺羟基磷灰石牙膏对早期龋的修复及吸附镉离子作用研究

马伟群, 黄建生, 徐平平

南方医科大学附属口腔医院广东省口腔医院,广东广州 510280

收稿日期:2014-04-04 发布日期:2019-04-10
通讯作者: 徐平平,主任医师,教授,博士生导师,电话:(020)84403311,E-mail:gdskqyykjk@163.com。
作者简介:马伟群(1986-),男,广东广州人,硕士研究生,电话:15521120940,E-mail:weiqun.ma@163.com。
基金资助:
国家自然科学基金资助项目(81271187);广东省科技计划资助项目(2011B080701099)

Effect of toothpaste containing hydroxyapatite on restoration of early stage caries and cadmium ion adsorption

MA Wei-qun, HUANG Jian-sheng, XU Ping-ping

Affiliated Stomatological Hospital,Southern Medical University, Guangdong Provincial Stomatological Hospital,Guangzhou,Guangdong 510280,China

Received:2014-04-04 Published:2019-04-10

摘要/Abstract

摘要： 通过掺羟基磷灰石(HA)牙膏对早期龋模型进行处理,应用扫描电镜和显微硬度计对再矿化效果进行分析,同时将掺HA牙膏和空白牙膏分别配成不同质量浓度的牙膏悬液,分别加入0.2 mg·L^-1的镉离子溶液中,静置24 h后去上清液用电感藕合等离子发射光谱仪测定残余镉离子的量,比较2种牙膏对水溶液中镉离子的吸附情况。结果显示,处理1和2周时掺HA牙膏组釉质的显微硬度分别为253.87±5.66和291.90±10.37,而空白牙膏组则分别仅为199.73±7.11和200.07±9.84,有统计学意义(P＜0.05);扫描电镜下可见HA处理对早期龋脱矿牙釉质再矿化作用明显;各质量浓度组的掺HA牙膏对镉离子的吸附率均高于空白牙膏。结果表明将HA掺入牙膏可提高其修复早期龋的作用,同时增强了对水中镉离子的吸附作用。

关键词: 牙膏, 羟基磷灰石, 龋齿, 重金属

Abstract: Models of tooth with early stage caries were treated with suspension of toothpaste containing hydroxyapatite (HA).The effect of re-mineralization of tooth enamel surface was assessed by scanning electron microscopy and microhardness value measurement.Cadmium ion solutions with initial mass concentration of 0.2 mg·L^-1 were mixed with toothpaste suspensions with and without addition of HA respectively and then been kept still for 24 h.The residual cadmium ion mass concentration of the supernatant was measured by inductively coupled plasma emission spectrometer and the adsorption effect of cadmium ion was calculated.Results showed that the toothpaste containing HA could significantly re-mineralize and improve the microhardness of artificial enamel caries.The Vicker's hardness values were 253.87±5.66 and 291.90±10.37 in HA group,higher than that of 199.73±7.11 and 200.07±9.84 in control group (P<0.05).The adsorption rate of cadmium ion of toothpaste containing HA is higher than that of the control group.

Key words: toothpaste, hydroxyapatite, caries, heavy metal

中图分类号:

TQ658.4+1

马伟群, 黄建生, 徐平平. 掺羟基磷灰石牙膏对早期龋的修复及吸附镉离子作用研究[J]. 日用化学工业, 2014, 44(5): 266-269.

MA Wei-qun, HUANG Jian-sheng, XU Ping-ping. Effect of toothpaste containing hydroxyapatite on restoration of early stage caries and cadmium ion adsorption[J]. China Surfactant Detergent & Cosmetics, 2014, 44(5): 266-269.

参考文献

[1] HUANG S B,GAO S S,YU H Y.Effect of nano-hydroxyapatite concentration on remineralization of initial enamel lesion in vitro [J].Biomed Mater,2009,4(3):811-819.
[2] KIM B I,JEONG S H,JANG S O,et al.Tooth whitening effect of toothpastes containing nano-hydroxyapatite [J].Key Engineering Materials,2006,309-311:541-544.
[3] ITTHAGARUN A,KING N M,CHEUNG Y M.The effect of nano-hydroxyapatite toothpaste on artificial enamel carious lesion progression:an in-vitro pH-cycling study [J].Hong Kong Dental Journal,2010,7(1):61-66.
[4] SHEHA R R.Sorption behavior of Zn(II) ions on synthesized hydroxyapatites [J].J Colloid Interface Sci,2007,310(1):18-26.
[5] NIWA M,SATO T,LI W,et al.Polishing and whitening properties of toothpaste containing hydroxyapatite [J].J Mater Sci Mater Med,2001,12(3):277-281.
[6] ORSINI G,PROCACCINI M,MANZOLI L,et al.A double-blind randomized-controlled trial comparing the desensitizing efficacy of a new dentifrice containing carbonate/hydroxyapatite nanocrystals and a sodium fluoride/potassium nitrate dentifrice [J].J Clin Periodontol,2010,37(6):510-517.
[7] YUAN P,SHEN X,LIU J,et al.Effects of dentifrice containing hydroxyapatite on dentinal tubule occlusion and aqueous hexavalent chromium cations sorption:a preliminary study [J].PLoS One,2012,7(12):45283-45290.
[8] PETER T,DANIELA L,MARTUS P.Enamel and dentine reminerali-zation by nano-hydroxyapatite toothpastes [J].J Dent,2011,39(6):430-437.
[9] MARSHALL G W,OLSON L M,LEE C V.SEM investigation of the variability of enamel surfaces after simulated clinical acid etching for pit and fissure sealants [J].J Dent Res,1975,54(6):1222-1231.
[10] SRINIVASAN N,KAVITHA M,LOGANATHAN S C.Comparison of the remineralization potential of CPP-ACP and CPP-ACP with 900 ppm fluoride on eroded human enamel:An in situ study [J].Arch Oral Biol,2010,55(7):541-544.
[11] 黄力子,唐林,徐如生,等.龋病发病机理的生物电化学理论:电化学人工龋模型的实验研究[J].中华口腔医学杂志,1997,32(1):35-37.
[12] 吕奎龙,滕立群,孟祥才,等.纳米羟基磷灰石牙膏对人工龋再矿化研究[J].黑龙江医药科学,2002(3):26-27.

[1]	段玉婷, 赵樱淼, 沈绥, 卢振西, 梁兵, 龙佳朋. 多孔氮化硼材料的制备及其吸附性能研究[J]. 日用化学工业（中英文）, 2024, 54(3): 273-281.
[2]	曹东霞, 周雷, 李家宏, 林长钦, 陈锦玲. 牙膏中可溶性/游离氟化物快速定量分析方法研究[J]. 日用化学工业（中英文）, 2024, 54(1): 38-44.
[3]	王继才, 简锐东, 谢宇, 陈晓斌, 周艺, 谭建华. 牙膏去除外源性色斑功效评价方法的标准化研究[J]. 日用化学工业（中英文）, 2023, 53(9): 1101-1107.
[4]	周雷,曹东霞,李家宏,苏哪锋,李文辉. 牙膏中不同形态氟化物的固体NMR研究[J]. 日用化学工业（中英文）, 2023, 53(8): 963-967.
[5]	高艳, 陈杰文, 肖蕾. 不同制膏法对牙膏流变性的影响研究[J]. 日用化学工业（中英文）, 2023, 53(11): 1299-1304.
[6]	郑丽霞, 高慧琴, 李飒, 郭从嘉, 郝倩莹, 吴国泰. 归芩牙膏中阿魏酸、黄芩苷含量测定及其药效学研究[J]. 日用化学工业（中英文）, 2023, 53(11): 1345-1350.
[7]	吴渊, 梁媛媛, 周志南, 黄甜甜, 夏琪琪, 刘鹏鹏. 基于扩增子测序分析益生菌牙膏中菌群多样性[J]. 日用化学工业（中英文）, 2023, 53(10): 1227-1232.
[8]	蒋菁,顾长明. 黄连上清胶囊联合抗敏牙膏治疗慢性牙周炎效果及对Th17/Treg、复发的影响[J]. 日用化学工业, 2022, 52(5): 539-544.
[9]	宫敬禹,邓全富,陈凤,董海德,许静,张旻. 牙膏产品安全评估数据的应用性研究[J]. 日用化学工业, 2022, 52(4): 425-430.
[10]	易瑞,徐春生. 密泡牙膏的试验研究[J]. 日用化学工业（中英文）, 2022, 52(11): 1214-1220.
[11]	张晓萍,王世芳. 高效液相色谱法测定牙膏中防腐剂含量[J]. 日用化学工业（中英文）, 2022, 52(11): 1248-1253.
[12]	李美舒,李希,宋秋华,刘春艳,倪嘉媛,潘涛. 基于微生物灭活芽孢的矿冶粉尘清洁皂的制备及性能研究[J]. 日用化学工业, 2022, 52(1): 15-19.
[13]	刘婧曦,郝二伟,杜正彩,秦健峰,侯小涛,邓家刚. 传统茶和别样茶在牙膏中的应用研究进展[J]. 日用化学工业, 2021, 51(3): 227-234.
[14]	吴莉,周娟娟,方方,冯有龙,曹玲. 电感耦合等离子体质谱法（ICP-MS）测定牙膏中多种元素[J]. 日用化学工业, 2021, 51(11): 1134-1141.
[15]	赵璇,高庆瑞,秦世丽,高立娣. 洗护发产品中8种重金属元素含量的测定[J]. 日用化学工业, 2021, 51(1): 78-82.

掺羟基磷灰石牙膏对早期龋的修复及吸附镉离子作用研究

Effect of toothpaste containing hydroxyapatite on restoration of early stage caries and cadmium ion adsorption

PDF (PC)

赞

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

Metrics

本文评价

推荐阅读 10