Abstract: H₆P₂Mo₉W₉O₆₂/Cu₃(BTC)₂ as a new catalyst was prepared by impregnation method.Fourier transformation infrared spectrum (FT-IR),X-ray diffraction (XRD),thermal gravimetry (TG) and scanning electron microscope (SEM) were used for characterization and measurement of its composition,structure,thermal stability and morphology.The reaction,with H₆P₂Mo₉W₉O₆₂/Cu₃(BTC)₂ as catalyst,for synthesis of ketal from cyclohexanone and ethylene glycol as starting materials was used as probe reaction,and the optimized synthesis conditions were found by orthogonal experiments as follows:fixing the amount of cyclohexanone as 0.2 mol;molar ratio,n(cyclohexanone)∶n(ethylene glycol)=1∶1.3;mass ratio of the catalyst to total reactants,0.3%;the reaction time,60 min;and amount of water stripping agent,6 mL.The yield of the product reaches 83.7%.Under similar reaction conditions,the yield of benzaldehyde ethylene glycol acetal reaches 70.1%;butanone glycol ketal,66.0%;butanone 1,2-propylene glycol ketal,62.1%;benzaldehyde 1,2-propanediol acetal,66.3%;and cyclohexanone 1,2-propylene glycol ketal,75.8%.Compared with that of catalysts H₄SiW₁₂O₄₀/MCM-48,activated carbon supported p-toluene sulfonic acid and Al-cross linked montmorillonite,H₆P₂Mo₉W₉O₆₂/Cu₃(BTC)₂ shows better catalytic performance.

Key words: perfume, acetals and ketals, catalytic synthesis, metal-organic framework