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日用化学工业(中英文) ›› 2025, Vol. 55 ›› Issue (6): 739-746.doi: 10.3969/j.issn.2097-2806.2025.06.008

• 开发与应用 • 上一篇    下一篇

油茶籽油-神经酰胺纳米乳液制备及研究

王兴婷1,2,施兆娟1,2,吴军1,2,袁传勋1,2,*(),金日生1,2   

  1. 1.合肥工业大学 食品与生物工程学院,安徽 合肥 230009
    2.农产品生物化工教育部工程研究中心,安徽 合肥 230009
  • 收稿日期:2024-06-12 修回日期:2025-05-28 出版日期:2025-06-22 发布日期:2025-07-01
  • 基金资助:
    安徽省科技重大专项(202103b06020025)

Preparation and study of Camellia oleifera seed oil-ceramide nanoemulsion

Xingting Wang1,2,Zhaojuan Shi1,2,Jun Wu1,2,Chuanxun Yuan1,2,*(),Risheng Jin1,2   

  1. 1. School of Food and Bioengineering, Hefei University of Technology, Hefei, Anhui 230009, China
    2. Engineering Research Center for Agriculture Biochemical Industry, Ministry of Education, Hefei, Anhui 230009, China
  • Received:2024-06-12 Revised:2025-05-28 Online:2025-06-22 Published:2025-07-01
  • Contact: E-mail: 3529669142@qq.com.

摘要: 为提高油茶籽油(Camellia oleifera seed oil,CSO)在化妆品领域的开发和应用,以CSO为化妆品基质油,并配伍神经酰胺(Ceramide,Cer),采用高压均质法制备并优化了CSO-Cer纳米乳液的最佳配方和条件。结果显示:在均质压力100 MPa,循环次数为7次,CSO质量分数为15%,Cer添加量为1%,氢化卵磷脂质量分数为4%,胆固醇质量分数为0.2%,甘油质量分数为25%的条件下,得到具有最优粒径和稳定性的纳米乳液。此乳液粒径为124.7 nm、多分散指数为0.108,Zeta电位为-55.7 mV。进一步测试发现,该CSO-Cer纳米乳液展现出良好的保湿特性和透皮性能。因此,基于CSO的CSO-Cer纳米乳液是一种潜在的新型功能性化妆品乳液,为后续CSO在化妆品领域的应用提供了重要的技术参考。

关键词: 油茶籽油, 神经酰胺, 纳米乳液, 保湿性, 透皮性

Abstract:

In order to enhance the development and application of Camellia oleifera seed oil (CSO) in the field of cosmetics, the study utilizes CSO as the cosmetic base oil and combines it with ceramide (Cer). High-pressure homogenization was employed to prepare and optimize the best formula and conditions for the CSO-Cer nanoemulsion. The results show that under the conditions of homogenization pressure at 100 MPa, 7 cycles, a CSO mass fraction of 15%, a Cer addition of 1%, a hydrogenated lecithin mass fraction of 4%, a cholesterol mass fraction of 0.2%, and a glycerol mass fraction of 25%, a nanoemulsion with optimal particle size and stability is obtained. This emulsion has a particle size of 124.7 nm, a polydispersity index of 0.108, and a Zeta potential of -55.7 mV. Further testing reveals that the CSO-Cer nano-emulsion exhibits excellent moisturizing and transdermal properties. Consequently, the CSO-based CSO-Cer nanoemulsion is a potential new type of functional cosmetic emulsion, providing significant technical reference for the subsequent application of CSO in the field of cosmetics.

Key words: Camellia oleifera seed oil, ceramide, nanoemulsion, moisturizing, transdermal

中图分类号: 

  • TQ658