液滴模板法构建疏水杂化囊用于包封SOD酶研究

doi:10.3969/j.issn.1001-1803.2021.10.001

Abstract

Abstract:

To solve the problems in the storage stability of bioactive molecules in cosmetics, the CaCO₃@Ca-Alg hybrid capsule with encapsulated superoxide dismutase （SOD） was prepared by droplet template method. Combined with the hydrophobic modification of the shell, the hydrophobic layer could prevent the infiltration of water molecules, thus improving the storage stability of the encapsulated substance. The results show that the SOD loaded hydrophobic hybrid capsule possesses uniform particle size and good monodispersity. The hydrophobicity of the hybrid capsule is improved with the increase of modification time. When the modification time is over 4 h, the hydrophobicity of the hybrid capsule remains stable. The relative enzyme activity of SOD encapsulated by this hybrid capsule is significantly higher than that of simple Ca-Alg capsule （the maximum difference can reach 300%）. The hydrophobic hybrid capsule can significantly improve the storage stability of SOD which will maintain more than 95% of the relative activity within 7 days.

Key words: droplet template method, hybrid capsule, enzyme immobilization, hydrophobicity

CLC Number:

TQ658

Deng Ningjun,Tang Qiming,Hong Meiying,Sun Mengmeng,Guo Ting,Meng Tao. Preparation of the hydrophobic hybrid capsule via droplet template method for encapsulating SOD[J].China Surfactant Detergent & Cosmetics, 2021, 51(10): 925-931.

Figures/Tables 8

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Preparation of the hydrophobic hybrid capsule via droplet template method for encapsulating SOD

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