高效液相色谱法分析脂肪醇聚氧乙烯醚衍生系列表面活性剂产品中的醇醚含量

doi:10.3969/j.issn.1001-1803.2019.12.011

摘要/Abstract

摘要：

建立了统一的液相色谱分析方法来测定基于醇醚衍生的系列表面活性剂产品中的醇醚含量,产品类别包括醇醚硫酸酯盐、醇醚糖苷、醇醚羧酸盐、醇醚柠檬酸酯盐。采用C₁₈色谱柱,甲醇-水梯度洗脱,使用流动相添加剂使醇醚色谱峰与干扰峰相互分离,蒸发光散射检测器检测。结果表明,相同碳链醇醚的回归方程系数接近,R ²皆大于0.999;方法精密度良好;测定各产品的平均回收率皆大于95%,准确度良好;方法在测定醇醚含量为0.5%~30%的样品时均显示出良好的适应性。醇醚含量随品种和样品的不同存在明显差异,测定方法同样适用于复配型产品。

关键词: 脂肪醇聚氧乙烯醚, 醇醚硫酸酯盐, 醇醚糖苷, 醇醚羧酸盐, 醇醚柠檬酸酯盐, 液相色谱分析

Abstract:

A uniform HPLC method was established for the determination of the fatty alcohol ethoxylates in the products of surfactants derived thereof. The surfactant products under investigation were alcohol ether sulfate, alkylethoxyglucoside, alcohol ether carboxylate, and fatty alcohol ether citrate monoester salt. The column was C₁₈ column and the gradient elution was performed with methanol-water solvent. The chromatographic peaks of fatty alcohol ethoxylates were separated from interference peaks by adding modification agent in the mobile phase. Evaporative light scattering detection (ELSD) was used. The results showed that the coefficients of the regression equations of fatty alcohol ethoxylates with the same alkyl group were close. The method showed good precision with the R ² being greater than 0.999; the method also showed good accuracy with the average recovery rate of each product being more than 95%. The method showed good adaptability for the samples with 0.5%-30% fatty alcohol ethoxylates. The method was also applicable to mixed products with different contents of fatty alcohol ethoxylates.

Key words: fatty alcohol ethoxylate, alcohol ether sulfate, alkylethoxyglucoside, alcohol ether carboxylate, fatty alcohol ether citrate monoester salt, liquid chromatography

中图分类号:

TQ423

张军,杨秀全,周媛. 高效液相色谱法分析脂肪醇聚氧乙烯醚衍生系列表面活性剂产品中的醇醚含量[J]. 日用化学工业, 2019, 49(12): 830-834.

ZHANG Jun,YANG Xiu-quan,ZHOU Yuan. Analysis of fatty alcohol ethoxylates in the serial products of fatty alcohol ethoxylate derived surfactants by HPLC[J]. China Surfactant Detergent & Cosmetics, 2019, 49(12): 830-834.

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参考文献 8

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AES	y=1.477x + 4.356 2	0.999 2	2.0%	99.5%	厂家A	0.5%	0
AES	y=1.477x + 4.356 2	0.999 2	2.0%	99.5%	厂家B	2.4%	2.5%
AEG	y=1.456x + 4.543 2	0.999 5	1.8%	96.8%	AEG050	4.5%	—
AEG	y=1.456x + 4.543 2	0.999 5	1.8%	96.8%	AEG300	29.8%	—
AEC	y=1.491 8x + 4.353 6	0.999 9	2.1%	98.6%	C₁₂₁₄-AEC-Na	3.7%	3.8%
AEC	y=1.462 7x + 4.337 6	0.999 4	2.0%	98.5%	C₁₂₁₄-AEC-H	6.1%	6.3%
AEO-EC	y=1.525 3x + 4.598 7	0.999 7	1.6%	97.6%	AEO₃-EC	4.8%	—
AEO-EC	y=1.514 6x + 4.259 3	0.999 5	1.9%	98.8%	AEO₆-EC	5.4%	—
样品	回归方程	线性（R²）	精密度RSD（n=5）	平均回收率（n=3）	醇醚含量
样品	回归方程	线性（R²）	精密度RSD（n=5）	平均回收率（n=3）		本文结果	对照方法

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