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日用化学工业（中英文）

日用化学工业 ›› 2015, Vol. 45 ›› Issue (11): 639-642.doi: 10.13218/j.cnki.csdc.2015.11.010

• 开发与应用 • 上一篇    下一篇

化妆品用微生物源天然防腐剂的抑菌效能研究

李馨恩1, 何秋星1, 区梓聪1, 方电力2, 关建云3, 赵红1   

  1. 1.广东药学院 医药化工学院,广东 中山 528458;
    2.诺斯贝尔(中山)无纺日化有限公司,广东 中山 442000;
    3.湛江市赛美生物科技有限公司,广东 湛江 524000
  • 收稿日期:2015-07-09 修回日期:2015-11-01 发布日期:2019-04-10
  • 作者简介:李馨恩(1991-),男,广东汕头人,硕士研究生,E-mail:leexinen@163.com。
  • 基金资助:
    2014年广东省本科高校应用化学专业综合改革试点项目

Antimicrobial effectiveness evaluation of natural microorganism source preservatives used for cosmetic formulation

LI Xin-en1, HE Qiu-xing1, OU Zi-cong1, FANG Dian-li2, GUAN Jian-yun3, ZHAO Hong1   

  1. 1.School of Chemistry and Chemical Engineering,Guangdong Pharmaceutical University,Zhongshan,Guangdong 528458,China;
    2.Nox-bellcow (Zhongshan) Nonwoven Chemical Co.,Ltd.,Zhongshan,Guangdong 442000,China;
    3.Zhanjiang Saimei Biological Technology Co.,Ltd.,Zhanjiang,Guangdong 524000,China
  • Received:2015-07-09 Revised:2015-11-01 Published:2019-04-10

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摘要： 以微生物源的嗜热链球菌发酵产物和曲霉发酵产物作为研究对象,根据其抑菌作用进行复配研究,参考美国个人护理品委员会(PCPC)的抑菌效能测试方法对乳液配方进行微生物挑战试验。结果表明,在乳液配方中,质量分数为0.5%的嗜热链球菌发酵产物和0.3%曲霉发酵产物可以使配方中的微生物菌落数在第14天降到100 CFU/g以下,可通过微生物挑战试验。

关键词: 天然防腐剂, 微生物源, 抑菌效能, 微生物挑战

Abstract: Two kinds of new natural microorganism source preservatives nominated Streptococus thermophilus Ferment and Aspergillus Ferment were taken as the object for research work.Formulation study based upon the bacterial inhibition action of the aforesaid preservatives was carried out.With reference of the bacterial inhibition efficacy test method of the American Personal Care Product Committee (PCPC),microbial challenge tests for emulsion formulations were processed.The test results demonstrated that an emulsion consisting of Streptococus thermophilus Ferment at 0.5% of mass fraction and Aspergillus Ferment at 0.3% of mass fraction can reduce the amount of microbial to be lower than 100 CFU/g on the 14th day and can pass the microbial challenge test meanwhile.

Key words: natural preservative, microorganism source, antimicrobial activity, microbial challenge test

中图分类号: 

  • TQ047.6