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日用化学工业（中英文）

日用化学工业 ›› 2017, Vol. 47 ›› Issue (7): 389-393.doi: 10.13218/j.cnki.csdc.2017.07.007

• 开发与应用 • 上一篇    下一篇

鲑鱼皮胶原蛋白肽的保湿性研究

孔惠1, 邢晓平2, 孙安琪1, 曹玉华1, 曹光群1   

  1. 1.江南大学 化学与材料工程学院,江苏 无锡 214122;
    2.盐城工学院 化学与生物工程学院,江苏 盐城 224051
  • 收稿日期:2017-02-28 发布日期:2019-03-20
  • 通讯作者: 曹玉华,教授,博士,电话:13382888922,E-mail:yuhuacao64@gmail.com。
  • 作者简介:孔 惠(1992-),女,江苏人,硕士研究生,电话:18762674562,E-mail:konghui87150133@126.com。
  • 基金资助:
    国家自然科学基金资助项目(21405133)

Study on moisturizing efficacy of collagen peptides from salmon skin

KONG Hui1, XING Xiao-ping2, SUN An-qi1, CAO Yu-hua1, CAO Guang-qun1   

  1. 1.School of Chemical and Material Engineering,Jiangnan University,Wuxi,Jiangsu 214122,China;
    2.School of Chemical and Biotechnology,Yancheng Institute of Technology,Yancheng,Jiangsu 224051,China
  • Received:2017-02-28 Published:2019-03-20

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摘要： 以鲑鱼皮为原料,采用酸浸-水提法得到鲑鱼皮明胶,并通过酶解制备了鲑鱼皮胶原蛋白肽,其中超过91.5%的鲑鱼皮胶原蛋白肽分子量小于1 000 Da。通过葡聚糖凝胶G-15层析柱分离出5种组分,按其分子量的大小依次为:S1>S2>S3>S4>S5。体外试验结果表明,相对湿度81%的环境下,吸湿性顺序为:S5>S4>甘油>鲑鱼皮胶原蛋白肽>S3>S2>S1≈透明质酸>鲑鱼皮明胶;保湿性顺序为:S5≈S4>S3>S2>甘油>鲑鱼皮胶原蛋白肽>S1>透明质酸>鲑鱼皮明胶。相对湿度43%的环境下,吸湿性顺序为:S5>甘油>S4>鲑鱼皮胶原蛋白肽≈S3>透明质酸>S2>S1>鲑鱼皮明胶;保湿性顺序为:S5>S4>甘油>S3≈鲑鱼皮胶原蛋白肽>透明质酸≈S2>S1>鲑鱼皮明胶。皮肤测试结果表明,涂抹含鲑鱼皮胶原蛋白肽的护肤品能够显著提高皮肤水分含量和降低经表皮失水率(TEWL),小分子鲑鱼皮胶原蛋白肽的保湿效果优于鲑鱼皮明胶。

关键词: 保湿化妆品添加剂, 胶原蛋白肽, 吸湿性, 保湿性

Abstract: Gelatin was extracted from salmon skin (hereinafter refers to as the gelatin) by acid leaching and water extraction.Then the gelatin were hydrolyzed enzymatically to prepare collagen peptides.More than 91.5% of the collagen peptides has a molecular weight of less than 1 000 Da.Five fractions from collagen peptides named S1,S2,S3,S4,S5 in decreasing order of molecular weight were separated by sephadex G-15.The study in vitro shows that when RH was 81%,the moisture absorption is a decreasing sequence as S5>S4>glycerol>collagen peptides>S3>S2>S1≈hyaluronic acid>the gelatin.The moisturizing effect shows a tendency of S5≈S4>S3>S2>glycerol>collagen peptides>S1>hyaluronic acid>the gelatin.When RH was 43%,the moisture absorption is a decreasing sequence as S5>glycerol>S4>collagen peptides≈S3>hyaluronic acid>S2>S1>the gelatin.The moisturizing effect is S5>S4>glycerol>S3≈collagen peptides>hyaluronic acid≈S2>S1>the gelatin.The skin test results show that collagen peptides from salmon skin significantly increase skin hydration and effectively decrease transepidermal water loss (TEWL),which is superior to that of the gelatin from salmon skin.

Key words: moisturizing cosmetic additive, collagen peptides, moisture absorption, moisturizing effect

中图分类号: 

  • TQ658.2