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日用化学工业 ›› 2016, Vol. 46 ›› Issue (7): 400-403.doi: 10.13218/j.cnki.csdc.2016.07.008

• 开发与应用 • 上一篇    下一篇

超声波辐射KF/K2CO3/γ-Al2O3催化合成肉桂酸的工艺研究

岳金方,罗志臣,丁乙,王学兰   

  1. 扬州工业职业技术学院 化学工程学院,江苏 扬州 225127
  • 出版日期:2016-07-22 发布日期:2019-04-18
  • 通讯作者: 罗志臣,教授,硕士,电话:15189870530,E-mail:lzc1990@sina.com。
  • 作者简介:岳金方(1978-),男,河北兴隆人,硕士,讲师。
  • 基金资助:
    江苏省第四期“333高层次人才培养工程”第三层次培养对象(苏人才办2011第8号)资助课题;扬州工业职业技术学院重点科研课题资助项目(2014A001);江苏高校品牌专业建设工程资助项目(PPZY2015B180)

Study on the synthesis of cinnamic acid catalyzed by KF/K2CO3/γ-Al2O3 under ultrasonic irradiation

YUE Jin-fang,LUO Zhi-chen,DING Yi,WANG Xue-lan   

  1. College of Chemical Engineering,Yangzhou Polytechnic Institute,Yangzhou,Jiangsu 225127,China
  • Online:2016-07-22 Published:2019-04-18

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摘要： 超声波辐射下,以KF/K2CO3/γ-Al2O3为催化剂,丙二酸和苯甲醛为原料,经Knoevenagel法合成肉桂酸。用IR和1H NMR及元素分析对产物进行了表征。考察了催化剂用量、苯甲醛与丙二酸摩尔比、超声波辐射功率和辐射时间等因素对肉桂酸收率的影响。结果显示,超声波辐射下,KF/K2CO3/γ-Al2O3具有良好的催化活性,且较佳反应条件为:苯甲醛用量20.4 mL (21.2 g,0.2 mol),n(苯甲醛)∶n(丙二酸)=1∶1.10,KF/K2CO3/γ-Al2O3用量4.5 g,超声波辐射功率120 W,超声波辐射时间60 min。在此条件下,肉桂酸的平均收率达到95%以上。

关键词: 肉桂酸, 超声波辐射, 催化合成

Abstract: Cinnamic acid was prepared by Knoevenagel method with KF/K2CO3/γ-Al2O3 as catalyst and benzaldehyde and propanedioic acid as starting materials under assistance of ultrasonic irradiation.IR,1H NMR and elemental analysis were used to characterize the product.The effects of catalyst dosage,molar ratio of benzaldehyde and propanedioic acid,ultrasonic irradiation power and irradiation time on the yield of cinnamic acid were studied.The results showed that KF/K2CO3/γ-Al2O3 catalyst displays good catalytic activity under ultrasonic irradiation.The optimal reaction conditions are as follows:for benzaldehyde 20.4 mL (21.2 g,0.2 mol),n(benzaldehyde)∶n(propanedioic acid)=1∶1.10,KF/K2CO3/γ-Al2O3 dosage 4.5 g,ultrasonic irradiation power 120 W,ultrasonic irradiation time 60 min;and the yield of cinnamic acid reaches higher than 95%.

Key words: cinnamic acid, ultrasonic irradiation, catalytic synthesis

中图分类号: 

  • TQ655