无机防晒剂

doi:10.13218/j.cnki.csdc.2014.12.156

Abstract

Abstract: Mechanism of inorganic sunscreen was briefly introduced.Relationship between particle size of inorganic sunscreen nanoparticles in sunscreen cosmetics and their UV shielding effect as well as the safety issue of inorganic sunscreen nanoparticles that was concerning seriously by peoples were summarized and focused on percutaneous penetration of TiO₂ and ZnO nanoparticles through human skin and their potential to cause phototoxicity.

Key words: sunscreen, nanoparticle, TiO₂, ZnO, phototoxicity, skin penetration

CLC Number:

TQ658

CAO Zhi, ZHANG Dao-jun. Inorganic sunscreening agents[J].China Surfactant Detergent & Cosmetics, 2014, 44(12): 700-705.

References

[1] 曹智,张治军.防晒化妆品长波紫外线防护效果的仪器评价法[J].日用化学工业,2009,39(3):196-199.
[2] OSTERWALDER U,SOHN M,HERZOG B.Global state of sunscreens [J].Photodermatology,Photoimmunology & Photomedicine,2014,30(2/3):62-80.
[3] MORABITO K,SHAPLEY N C,STEELEY K G,et al.Review of sunscreen and the emergence of non-conventional absorbers and their applications in ultraviolet protection [J].International Journal of Cosmetic Science,2011,33(5):385-390.
[4] GILABERTE Y,CARRASCOSA J M.Sun protection in children:realities and challenges [J].Actas Dermo-Sifiliográficas,2014,105(3):253-262.
[5] WANG S Q,TOOLEY I R.Photoprotection in the era of nanotechnology [J].Seminars in Cutaneous Medicine and Surgery,2011,30(4):210-213.
[6] SAYRE R M,KOLLIAS N,ROBERTS R L,et al.Physical sunscreens [J].Journal of the Society of Cosmetic Chemists,1990,41(2):103-109.
[7] DRANSFIELD G P.Inorganic sunscreens [J].Radiation Protection Dosimetry,2000,91:271-273.
[8] INNES B,TSUZUKI T,DAWKINS H,et al.Nanotechnology and the cosmetic chemist [J].Cosmetics,Aerosols and Toiletries in Australia,2002,15(5):10-24.
[9] SHAATH N.Sunscreens:Regulations and commercial development [M].3rd ed.Boca Raton:Taylor & Francis,2005:246-248.
[10] LIM H W,DRAELOS Z D.Clinical guide to sunscreens and photoprotection [M].New York:Informa Healthcare USA,2009:11-38.
[11] BUTLER M K,PROW T W,GUO Y N,et al.High-pressure freezing/freeze substitution and transmission electron microscopy for charac-terization of metal oxide nanoparticles within sunscreens [J].Nanomedicine,2012,7(4):541-551.
[12] SCHILLING K,BRADFORD B,CASTELLI D,et al.Human safety review of “nano” titanium dioxide and zinc oxide [J].Photochemical & Photobiological Sciences,2010,9(4):495-509.
[13] POPOV A P,LADEMANN J,PRIEZZHEV A V,et al.Effect of size of TiO₂ nanoparticles embedded into stratum corneum on ultraviolet-A and ultraviolet-B sun-blocking properties of the skin [J].Journal of Biomedical Optics,2005,10(6):064037.
[14] NASIR A,FRIEDMAN A,WANG S.Nanotechnology in dermatology [M].New York:Springer,2013:9-18.
[15] MORE B D.Physical sunscreens:On the comeback trail [J].Indian Journal of Dermatology,Venereology and Leprology,2007,73(2):80-85.
[16] WIECHERS S,BIEHL P,LUVEN C,et al.Titanium dioxide particle size vs.sun protection performance [J].Cosmetics & Toiletries,2013,128(5):332-339.
[17] KISS B,BIRO T,CZIFRA G,et al.Investigation of micronized titanium dioxide penetration in human skin xenografts and its effect on cellular functions of human skin-derived cells [J].Experimental Dermatology,2008,17(8):659-667.
[18] WAKEFIELD G,LIPSCOMB S,HOLLAND E,et al.The effects of manganese doping on UVA absorption and free radical generation of micronised titanium dioxide and its consequences for the photostability of UVA absorbing organic sunscreen components [J].Photochemical & Photobiological Sciences,2004,3(7):648-652.
[19] LINSEBIGLER A L,LU G,YATES J T.Photocatalysis on TiO₂ surfaces:principles,mechanisms,and selected results [J].Chemical Reviews,1995,95(3):735-758.
[20] UCHINO T,TOKUNAGA H,ANDO M,et al.Quantitative determination of OH radical generation and its cytotoxicity induced by TiO₂^-UVA treatment [J].Toxicology in Vitro,2002,16(5):629-635.
[21] DUNFORD R,SALINARO A,CAI L,et al.Chemical oxidation and DNA damage catalysed by inorganic sunscreen ingredients [J].FEBS Letters,1997,418(1/2):87-90.
[22] MENZEL F,REINERT T,VOGT J,et al.Investigations of percutaneous uptake of ultrafine TiO₂ particles at the high energy ion nanoprobe LIPSION [J].Nuclear Instruments and Methods in Physics Research Section B:Beam Interactions with Materials and Atoms,2004,219-220:82-86.
[23] WAMER W G,YIN J,WEI R R.Oxidative damage to nucleic acids photosensitized by titanium dioxide [J].Free Radical Biology and Medicine,1997,23(6):851-858.
[24] XUE C,WU J,LAN F,et al.Nano titanium dioxide induces the generation of ROS and potential damage in HaCaT cells under UVA irradiation [J].Journal of Nanoscience and Nanotechnology,2010,10(12):8500-8507.
[25] HIDAKA H,KOBAYASHI H,KOIKE T,et al.DNA damage photoinduced by cosmetic pigments and sunscreen agents under solar exposure and artificial UV illumination [J].Journal of Oleo Science,2006,55(5):249-261.
[26] YANG Q,MA Y.Irradiation-enhanced cytotoxicity of zinc oxide nanoparticles [J].International Journal of Toxicology,2014,33(3):187-203.
[27] DUFOUR E K,KUMARAVEL T,NOHYNEK G J,et al.Clastogenicity,photo-clastogenicity or pseudo-photo-clastogenicity:Genotoxic effects of zinc oxide in the dark,in pre-irradiated or simultaneously irradiated Chinese hamster ovary cells [J].Mutation Research/Genetic Toxicology and Environmental Mutagenesis,2006,607(2):215-224.
[28] SHEN C,TURNEY T W,PIVA T J,et al.Comparison of UVA-induced ROS and sunscreen nanoparticle-generated ROS in human immune cells [J].Photochemical & Photobiological Sciences,2014,13(5):781-788.
[29] TSUZUKI T,HE R,WANG J,et al.Reduction of the photocatalytic activity of ZnO nanoparticles for UV protection applications [J].International Journal of Nanotechnology,2012,9(10):1017-1029.
[30] LIVRAGHI S,CORAZZARI I,PAGANINI M C,et al.Decreasing the oxidative potential of TiO₂ nanoparticles through modification of the surface with carbon:a new strategy for the production of safe UV filters [J].Chemical Communications,2010,46(44):8478-8480.
[31] PAN Z,LEE W,SLUTSKY L,et al.Adverse effects of titanium dioxide nanoparticles on human dermal fibroblasts and how to protect cells [J].Small,2009,5(4):511-520.
[32] FISICHELLA M,BERENGUER F,STEINMETZ G,et al.Intestinal toxicity evaluation of TiO₂ degraded surface-treated nanoparticles:A combined physico-chemical and toxicogenomics approach in caco-2 cells [J].Particle and Fibre Toxicology,2012,9:18.
[33] CAO Z,ZHANG Z.Deactivation of photocatalytically active ZnO nanoparticle and enhancement of its compatibility with organic compounds by surface-capping with organically modified silica [J].Applied Surface Science,2011,257(9):4151-4158.
[34] PINNELL S R.Cutaneous photodamage,oxidative stress,and topical antioxidant protection [J].Journal of the American Academy of Dermatology,2003,48(1):1-22.
[35] ZHANG X,WANG F,LIU B,et al.Adsorption of DNA oligonucleotides by titanium dioxide nanoparticles [J].Langmuir,2014,30(3):839-845.
[36] FILIPE P,SILVA J N,SILVA R,et al.Stratum corneum is an effective barrier to TiO₂ and ZnO nanoparticle percutaneous absorption [J].Skin Pharmacology and Physiology,2009,22(5):266-275.
[37] SCHILLING K,BRADFORD B,CASTELLI D,et al.Human safety review of “nano” titanium dioxide and zinc oxide [J].Photochemical & Photobiological Sciences,2010,9(4):495-509.
[38] GILBERT E,PIROT F,BERTHOLLE V,et al.Commonly used UV filter toxicity on biological functions:review of last decade studies [J].International Journal of Cosmetic Science,2013,35(3):208-219.
[39] JANSEN R,OSTERWALDER U,WANG S Q,et al.Photoprotection:part II.Sunscreen:Development,efficacy,and controversies [J].Journal of the American Academy of Dermatology,2013,69(6):861-867.
[40] MIQUEL-JEANJEAN C,CREPEL F,RAUFAST V,et al.Penetration study of formulated nanosized titanium dioxide in models of damaged and sun-irradiated skins [J].Photochemistry and Photobiology,2012,88(6):1513-1521.
[41] MONTEIRO-RIVIERE N A,WIENCH K,LANDSIEDEL R,et al.Safety evaluation of sunscreen formulations containing titanium dioxide and zinc oxide nanoparticles in UVB sunburned skin:an in vitro and in vivo study [J].Toxicological Sciences,2011,123(1):264-280.
[42] GAMER A O,LEIBOLD E,VAN RAVENZWAAY B.The in vitro absorption of microfine zinc oxide and titanium dioxide through porcine skin [J].Toxicology in Vitro,2006,20(3):301-307.
[43] WATKINSON A,BUNGE A,HADGRAFT J,et al.Nanoparticles do not penetrate human skin:A theoretical perspective [J].Pharmaceutical Research,2013,30(8):1943-1946.
[44] NOHYNEK G J,DUFOUR E K.Nano-sized cosmetic formulations or solid nanoparticles in sunscreens:a risk to human health? [J].Archives of Toxicology,2012,86(7):1063-1075.
[45] NOHYNEK G J,LADEMANN J,RIBAUD C,et al.Grey goo on the skin? Nanotechnology,cosmetic and sunscreen safety [J].Critical Reviews in Toxicology,2007,37(3):251-277.
[46] POPOV A P,ZVYAGIN A V,LADEMANN J,et al.Designing inorganic light-protective skin nanotechnology products [J].Journal of Biomedical Nanotechnology,2010,6(5):432-451.
[47] LADEMANN J,KNORR F,RICHTER H,et al.Hair follicles:An efficient storage and penetration pathway for topically applied substances.Summary of recent results obtained at the Center of Experimental and Applied Cutaneous Physiology,Charite-Universitatsmedizin Berlin,Germany [J].Skin Pharmacology and Physiology,2008,21(3):150-155.

Inorganic sunscreening agents

PDF (PC)

Like

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Metrics

Comments

Recommended 10

[1]	Na Ta, Mengxin Feng, Jiamin Gao, Fenglan Zhang, Gangli Wang. Supervision and use analysis of sunscreen with potential endocrine disruption risk [J]. China Surfactant Detergent & Cosmetics, 2024, 54(3): 337-343.
[2]	Yanna Tang, Zizhen Chen. Degradation of tetracycline hydrochloride by BaTiO₃-TiO₂ composite photocatalyst and its mechanism [J]. China Surfactant Detergent & Cosmetics, 2024, 54(2): 175-180.
[3]	Pei Liu, Ting Pan, Xiaomei Pei, Binglei Song, Jianzhong Jiang, Zhenggang Cui, Bernard P. Binks. Dual-responsive oil-in-water emulsions co-stabilized by a nonionic-anionic Bola surfactant and silica nanoparticles [J]. China Surfactant Detergent & Cosmetics, 2024, 54(1): 1-15.
[4]	Chang Xiangling, Chai Fei. Preparation and performance study of zinc oxide nanocomposite antibacterial materials [J]. China Surfactant Detergent & Cosmetics, 2023, 53(9): 1051-1056.
[5]	Wang Zhuliang,Guan Shuping,Zhang Min,Yang Jie,Li Yongji. The size and morphology control of Fe₃O₄ nanoparticles synthesized by solvothermal method using polyethylene glycol and diethylene glycol [J]. China Surfactant Detergent & Cosmetics, 2023, 53(8): 882-890.
[6]	Feng Li,Zou Baisong. Simultaneous determination of 11 components in Danzhi Fangshaishuang SFP50 by HPLC [J]. China Surfactant Detergent & Cosmetics, 2023, 53(8): 968-975.
[7]	Tan Wenbo,Meng Yanqiang. Synthesis and UV absorption capacity of nano-zinc oxides [J]. China Surfactant Detergent & Cosmetics, 2023, 53(8): 908-914.
[8]	He Huan,Sun Lei,Wen Xuehua,Jiang Yaxue,Liu Min,Feng Keran. Research on the management system of sunscreen products in Japan and the inspiration for China [J]. China Surfactant Detergent & Cosmetics, 2023, 53(8): 935-944.
[9]	Zhang Zhenyang, He Yunyang. Syntheses of ZnO nanoparticles and their degradation activities on tetracycline hydrochloride [J]. China Surfactant Detergent & Cosmetics, 2023, 53(7): 781-788.
[10]	Wang Min, Li Mengyue, Li Xiaoyi, Liu Qi, Zhao Hua, Zhao Fengnian. On-site and rapid electrochemical method for chloramphenicol detection in facial masks [J]. China Surfactant Detergent & Cosmetics, 2023, 53(7): 802-807.
[11]	Li Xi, Aidarova Saule, Yin Xia, Issakhov Miras, Xu Derong, Kang Wanli. Research progress of fluorescent nanomaterials [J]. China Surfactant Detergent & Cosmetics, 2023, 53(5): 551-559.
[12]	Deng Mengjie, Yi Guobin, Lv Ran, Liu Yafeng, Ye Dawei, Chen Jiazhi. Ferulic acid nanoethosomes: preparation, characterization, and performance of skin penetration in vitro [J]. China Surfactant Detergent & Cosmetics, 2023, 53(11): 1285-1292.
[13]	Ta Na, Yu Zhenxi, Gao Jiamin, Zhang Fenglan, Wang Gangli. Analysis on registration of imported sunscreen cosmetics in China in 2017—2021 [J]. China Surfactant Detergent & Cosmetics, 2023, 53(10): 1204-1210.
[14]	Wang Lei, Wu Yue, Tian Dong. Determination of five benzotriazole UV absorbers in cosmetics by ultrasonic extraction and high performance liquid chromatography [J]. China Surfactant Detergent & Cosmetics, 2023, 53(1): 109-114.
[15]	Wang Chunyu, Wang Huijuan, Fan Shiqiang, Liu Yang. Research progress on functional application of lignin nanoparticles [J]. China Surfactant Detergent & Cosmetics, 2023, 53(1): 92-99.