Abstract: Protection action of mandshurin with respect to human skin fibroblastic strain (HSF) caused by ultraviolet irradiation as well as sunscreening performance of its formulated product was investigated via volunteers' body test method.Results showed that,as compared with the control group that is cultivated under conventional way,under same other conditions,the ultraviolet irradiation suppresses the growth of HSF significantly,while the addition of mandshurin improves the growth of HSF apparently.Via volunteers' body tests,the sun protection factor (SPF) of mandshurin sunscreening cosmetic cream was measured as 16 in-vivo.Obviously mandshurin sunscreening cosmetic cream displays good ultraviolet resistance action conspicuously.Hopefully,mandshurin might be added into cosmetics as sunscreening agent to resist ultraviolet irradiation of moderate sunshining.

Key words: sunscreening agent, mandshurin, coumarin, anti-ultraviolet