Pickering乳液聚合法制备复合防晒微球体

doi:10.3969/j.issn.1001-1803.2021.01.007

日用化学工业 ›› 2021, Vol. 51 ›› Issue (1): 38-43.doi: 10.3969/j.issn.1001-1803.2021.01.007

Pickering乳液聚合法制备复合防晒微球体

喻明英(),王靖(),杨成,曹光群

江南大学化学与材料工程学院,江苏无锡 214122

收稿日期:2020-06-16 修回日期:2021-01-04 出版日期:2021-01-22 发布日期:2021-01-20
通讯作者: 王靖
作者简介:喻明英（1995-）,湖南人,硕士研究生,电话：17851302790,E-mail: 17851302790@163.com。
基金资助:
国家自然科学基金资助项目(51802123)

Preparation of sunscreening composite microspheres by Pickering emulsion polymerization

YU Ming-ying(),WANG Jing(),YANG Cheng,CAO Guang-qun

School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu 214122, China

Received:2020-06-16 Revised:2021-01-04 Online:2021-01-22 Published:2021-01-20
Contact: Jing WANG

摘要/Abstract

摘要：

设计了一种表面负载物理防晒剂TiO₂、内部包埋化学防晒剂阿伏苯宗（AVB）的PMMA微球体（TiO₂@PMMA-AVB）,并以TiO₂纳米粒子为Pickering乳化剂,利用Pickering乳液聚合法,在无表面活性剂的条件下一步法制备了TiO₂@PMMA-AVB复合防晒微球体。紫外光透过率、光稳定性、体外透皮以及感官测试结果表明该微球体具有提高紫外防护效果、增加AVB光稳定性以及减少AVB经皮吸收;且微球粉体细腻易洗去,能改善TiO₂泛白的效果。该微球体结构可以避免TiO₂与AVB的直接接触,并且表面TiO₂可以为微球体内AVB过滤一部分紫外线,从而延长AVB的使用寿命。

关键词: Pickering乳液聚合, 复合防晒微球, 纳米TiO₂, 阿伏苯宗, 光稳定性, 透皮作用

Abstract:

The microspheres loaded with TiO₂ and embedding avobenzone （AVB） were prepared in one step. First, amphiphilic TiO₂ nanoparticles were prepared and then an O/W Pickering emulsion stabilized by these nanoparticles was successfully used to prepare the microspheres. The results of UV transmittance, light stability, in vitro transdermal and sensory tests showed that, the microspheres could improve the ability of UV protection and the light stability of avobenzone, and reduce the transdermal absorption of AVB. Moreover, the microsphere powder was delicate and easy to be washed away, and it could improve the whitening effect of TiO₂. This structure made TiO₂ nanoparticles evenly distributed and avoided direct contact between TiO₂ and AVB; the nano-TiO₂ on the surface of microspheres could filter a part of UV, so the service life of AVB in the microsphere could be prolonged.

Key words: Pickering emulsion polymerization, composite sunscreening microsphere, nano-TiO₂, avobenzone, light stability, transdermal effect

中图分类号:

TQ658

喻明英,王靖,杨成,曹光群. Pickering乳液聚合法制备复合防晒微球体[J]. 日用化学工业, 2021, 51(1): 38-43.

YU Ming-ying,WANG Jing,YANG Cheng,CAO Guang-qun. Preparation of sunscreening composite microspheres by Pickering emulsion polymerization[J]. China Surfactant Detergent & Cosmetics, 2021, 51(1): 38-43.

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项目	名称	w/%	项目	名称	w/%
油相	1, 3-丁二醇	7.00	水相	硬脂酸	3.0
	二氧化钛	按微球负载量计算		角鲨烷	10
	三乙醇胺	1.00		白凡士林	5.0
	EDTA二钠	0.05		十八醇	3.0
	纯水	余量		阿伏苯宗	5
	香精,防腐剂	–		单硬脂酸甘油酯	3.0
	其他	对应的微球基质		聚二甲基硅氧烷	1.0

Pickering乳液聚合法制备复合防晒微球体

Preparation of sunscreening composite microspheres by Pickering emulsion polymerization

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