Abstract: Interactions between ionic liquid surfactants and bioactive molecules were summarized in three aspects.Hydrophobic ionic liquid surfactants can form inclusion complexes with β-cyclodextrin (β-CD) according to ratio of 1∶1,1∶2 or 2∶1;while hydrophilic ionic liquid surfactants cannot.The cmc and adsorption of ionic liquid surfactants at interface are affected by the inclusion complexes.The molecular structure and adsorption of protein at the interface between water and oil are affected by the interaction of ionic liquid surfactants with varied kinds of protein,such as bovine serum albumin,β-casein and lysozyme.The interactions between ionic liquid surfactants and DNA are caused by electrostatic attraction and hydrophobic action.

Key words: surfactant, ionic liquid, cyclodextrin, protein, DNA