高效液相色谱法分析脂肪醇聚氧乙烯醚衍生系列表面活性剂产品中的醇醚含量

doi:10.3969/j.issn.1001-1803.2019.12.011

Abstract

Abstract:

A uniform HPLC method was established for the determination of the fatty alcohol ethoxylates in the products of surfactants derived thereof. The surfactant products under investigation were alcohol ether sulfate, alkylethoxyglucoside, alcohol ether carboxylate, and fatty alcohol ether citrate monoester salt. The column was C₁₈ column and the gradient elution was performed with methanol-water solvent. The chromatographic peaks of fatty alcohol ethoxylates were separated from interference peaks by adding modification agent in the mobile phase. Evaporative light scattering detection (ELSD) was used. The results showed that the coefficients of the regression equations of fatty alcohol ethoxylates with the same alkyl group were close. The method showed good precision with the R ² being greater than 0.999; the method also showed good accuracy with the average recovery rate of each product being more than 95%. The method showed good adaptability for the samples with 0.5%-30% fatty alcohol ethoxylates. The method was also applicable to mixed products with different contents of fatty alcohol ethoxylates.

Key words: fatty alcohol ethoxylate, alcohol ether sulfate, alkylethoxyglucoside, alcohol ether carboxylate, fatty alcohol ether citrate monoester salt, liquid chromatography

CLC Number:

TQ423

ZHANG Jun,YANG Xiu-quan,ZHOU Yuan. Analysis of fatty alcohol ethoxylates in the serial products of fatty alcohol ethoxylate derived surfactants by HPLC[J].China Surfactant Detergent & Cosmetics, 2019, 49(12): 830-834.

Figures/Tables 6

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Tab. 1

Tab. 2

References 8

[1]	Jiang Feiguo, Zhu Hong, Chen Yaowu , et al. Synjournal of fatty alcohol polyethoxylates with narrow ethoxymer distribution[J]. Polymer Bulletin, 2014 ( 12) : 118-123.
[2]	Shen Hong, Yang Guang, Zhan Jianwei , et al. Research progress on narrow distribution fatty alcohol ether sulfates[J]. Detergent & Cosmetics, 2016,39(8) : 31-33. doi: 10.3168/jds.2019-17389 pmid: 31864737
[3]	Zhang Yuanjun, Yang Xiuquan, Yang Qingli , et al. The preparation and complex properties of alkylethoxyglucoside[J]. Chemical Research and Application, 2009,21(8) : 1108-1113. doi: 10.1007/s00216-019-02330-y pmid: 31853602
[4]	Li Yunling, Song Yongbo, Hou Suzhen , et al. Green preparation and properties of alcohol ether carboxylate[J]. Detergent & Cosmetics, 2014,37(10) : 21-25. doi: 10.3168/jds.2019-17389 pmid: 31864737
[5]	Niu Shaoyong, Yang Xiuquan, Bai Liang , et al. Performance determination of the citric acid ester surfactants[J]. Chemistry & Bioengineering, 2012,29(7) : 86-88. doi: 10.1007/s11356-019-07177-5 pmid: 31865584
[6]	Han Jianying . Determination of the degree of substitution of carboxymethyl groups(DS)of alcohol ether carboxylate[J]. Applied Chemical Industry, 2015,44(8) : 1556-1557.
[7]	Guo Lin, Tong Tianzhong, Chen Kongchang . Separation and determination of alcohol-or alkylphenol ethoxy carboxylate acids by reversed-phase ion pair high performance liquid chromatography[J]. Chinese Journal of Analytieal Chemistry, 2000,28(4) : 407-410.
[8]	Zhang Jun, Yang Xiuquan, Zhou Yuan , et al. HPLC determination of components in alkylethoxyglucoside citric ester products[J]. Physical Testing and Chemical Analysis (Part B: Chemical Analysis), 2013,49(7) : 867-869.

AES	y=1.477x + 4.356 2	0.999 2	2.0%	99.5%	厂家A	0.5%	0
AES	y=1.477x + 4.356 2	0.999 2	2.0%	99.5%	厂家B	2.4%	2.5%
AEG	y=1.456x + 4.543 2	0.999 5	1.8%	96.8%	AEG050	4.5%	—
AEG	y=1.456x + 4.543 2	0.999 5	1.8%	96.8%	AEG300	29.8%	—
AEC	y=1.491 8x + 4.353 6	0.999 9	2.1%	98.6%	C₁₂₁₄-AEC-Na	3.7%	3.8%
AEC	y=1.462 7x + 4.337 6	0.999 4	2.0%	98.5%	C₁₂₁₄-AEC-H	6.1%	6.3%
AEO-EC	y=1.525 3x + 4.598 7	0.999 7	1.6%	97.6%	AEO₃-EC	4.8%	—
AEO-EC	y=1.514 6x + 4.259 3	0.999 5	1.9%	98.8%	AEO₆-EC	5.4%	—
样品	回归方程	线性（R²）	精密度RSD（n=5）	平均回收率（n=3）	醇醚含量
样品	回归方程	线性（R²）	精密度RSD（n=5）	平均回收率（n=3）		本文结果	对照方法

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Analysis of fatty alcohol ethoxylates in the serial products of fatty alcohol ethoxylate derived surfactants by HPLC

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