N-酰基肌氨酸钠的合成工艺现状

doi:10.13218/j.cnki.csdc.2016.01.011

Abstract

Abstract: Synthesis process technology and analytical method of sodium N-acyl sarcosinate product were summarized.Indirect synthesis method (Schotten-Baumann condensation) was emphatically introduced.In accordance to the operating conditions,the process can be classified into three ways,dropwise addition of sodium hydroxide aqueous solution and fatty acyl chloride into aqueous phase of sodium sarcosinate solution,dropwise addition of sodium hydroxide aqueous solution and fatty acyl chloride into a mixed phase composed of sodium sarcosinate solution and an organic solvent as well as addition of all sodium hydroxide solution first into the aqueous phase of sodium sarcosinate solution and then dropwise addition of fatty acyl chloride into the mixed aqueous phase.Advantages and disadvantages of the three ways were discussed.Various analysis methods for sodium N-acyl sarcosinate product quality control were compared.

Key words: sodium N-acyl sarcosinate, synthesis process, analysis method

CLC Number:

TQ423.11

YU Fang. Current situation with respect to synthesis technology of sodium N-acyl sarcosinate[J].China Surfactant Detergent & Cosmetics, 2016, 46(1): 53-57.

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Current situation with respect to synthesis technology of sodium N-acyl sarcosinate

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