墨藻胶对皮肤水合及屏障功能的促进作用研究

doi:10.13218/j.cnki.csdc.2017.12.011

Abstract

Abstract: The moisturizing performance of Gmoist Sea-Gel (GSG) was evaluated based-upon 14 healthy volunteers.It was found that skin moisture content (CM) markedly increased and TEWL effectively decreased after Gmoist Sea-Gel (GSG) applied for 7 d.Then using real-time fluorescence quantitative PCR technology,HaCaT cells were cultured with GSG to study six genes expression level related to skin hydration and barrier function.Results show that GSG significantly promotes the INV,TG-1,FLG and CASP-14 mRNAs expression after 24 hours treatment.GSG can upgrade cornified cell envelope related genes expression,promote the degradation of filaggrin into natural moisturizing factors to strengthen skin hydration and barrier function.

Key words: moisturizing cosmetic additive, Gmoist Sea-Gel, skin barrier

CLC Number:

TQ658.2

LU Yi-na, YANG Ya-di, XIE Zhi-yong, TIAN Jun. Promoting effect of Gmoist Sea-Gel on skin hydration and barrier function[J].China Surfactant Detergent & Cosmetics, 2017, 47(12): 709-712.

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Promoting effect of Gmoist Sea-Gel on skin hydration and barrier function

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