天然椰子油提取物对H2O2诱导的HSF细胞氧化损伤的保护作用

doi:10.13218/j.cnki.csdc.2017.09.008

Abstract

Abstract: The human skin fibroblasts (HSF) cell morphology was observed by inverted biological microscope,the cell viability was detected by MTT method,and the intracellular ROS level,the intracellular total antioxidation capacity and the activity of antioxidation enzyme (SOD,CAT and GSH-Px) were examined for investigating the protective effects of virgin coconut oil extracts on oxidative damage of HSF cells induced by H₂O₂.Results show that the virgin coconut oil extracts could protect HSF cells from oxidative damage induced by H₂O₂ at mass concentration range of 12.5 to 50 mg/L with a concentration dependent manner.Virgin coconut oil extracts could inhibit the cell morphological damage induced by H₂O₂ and improve the survival rate of the cells.In addition,virgin coconut oil extracts could protect HSF cells from oxidative damage induced by oxidative stress through decreasing the intracellular ROS level,increasing intracellular total antioxidant capacity and the enzyme activity of SOD,CAT and GSH-Px.

Key words: cosmetic ingredient, virgin coconut oil, HSF cells, antioxidant, anti-aging

CLC Number:

TQ658

SONG Fei, WANG Hui, TANG Min-min, SHEN Xiao-jun, ZHANG Yu-feng, DENG Fu-ming. Protective effects of virgin coconut oil extracts on oxidative damage of human skin fibroblasts cells induced by H₂O₂[J].China Surfactant Detergent & Cosmetics, 2017, 47(9): 517-521.

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Protective effects of virgin coconut oil extracts on oxidative damage of human skin fibroblasts cells induced by H₂O₂

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Protective effects of virgin coconut oil extracts on oxidative damage of human skin fibroblasts cells induced by H2O2

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Protective effects of virgin coconut oil extracts on oxidative damage of human skin fibroblasts cells induced by H₂O₂