O/W/Si多重防晒乳液的制备及性能研究

doi:10.3969/j.issn.2097-2806.2024.12.006

Abstract

Abstract:

To solve the greasiness and irritation risks brought about by organic sun-screening agents in sunscreen emulsions, in this work, a sunscreen O/W/Si multiple emulsion was prepared by two-step emulsification method, in which the outer oil phase was silicone oil and the inner oil phase was solid lipid nanoparticles coated with organic sun-screening agent. Several influencing factors on the formation and stability of the emulsion were analyzed, including inorganic salts, the volume fraction of outer oil phase （silicone oil）, and the dosage of W/O emulsifier. The in vitro sunscreen performance, water resistance and skin permeability of different types of sunscreen emulsions were further studied. The results showed that the sunscreen O/W/Si multiple emulsion containing 22.5% silicone oil, 2.5% emulsifier and 0.2% NaCl had the best stability under the experimental conditions. The SPF value and water resistance of sunscreen O/W/Si multiple emulsion were slightly higher than those of sunscreen W/O emulsion, but significantly higher than those of sunscreen O/W emulsion. Compared with sunscreen W/O emulsion, the in vitro transdermal permeability of organic sun-screening agent in sunscreen O/W/Si multiple emulsion was reduced by approximately 60%, indicative of higher safety and good application prospect in sunscreen cosmetics.

Key words: O/W/Si multiple emulsion, organic sunscreen, sun protection performance, water resistance, percutaneous permeability

CLC Number:

TQ658

Wanping Zhang, Lv Zhou, Zihao Gao, Haiyang Zhu. Study on the preparation and properties of sunscreen O/W/Si multiple emulsion[J].China Surfactant Detergent & Cosmetics, 2024, 54(12): 1447-1455.

Figures/Tables 14

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References 23

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组相	原料名称	w/%
A（外油相）	PEG-10聚二甲基硅氧烷	2.5
	环五（和）环六聚二甲基硅氧烷	25.0
	聚二甲基硅氧烷	5.0
B（水相）	水	To 100.0
	甘油	5.0
	防晒剂-SLN	20.0
	氯化钠	0.2
C（防腐剂）	苯氧乙醇	0.5

商品名	INCI中文名	HLB值
KF-6017	PEG-10聚二甲基硅氧烷	4.5
KF-6038	月桂基PEG-9聚二甲基硅氧乙基聚二甲基硅氧烷	3
EM 90	鲸蜡基PEG/PPG-10/1聚二甲基硅氧烷	5

Study on the preparation and properties of sunscreen O/W/Si multiple emulsion

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乳液类型	SPF _{In vitro}
O/W/Si	28.24
W/O	24.12
O/W	14.50