祛斑美白类化妆品功效成分的研究现状

doi:10.3969/j.issn.2097-2806.2024.01.011

Abstract

Abstract:

Excessive accumulation of melanin pigments may result in skin-related disorders such as post inflammatory pigmentation, solar lentigo, melasma and freckles. The mechanism of action of whitening cosmetics is related to the inhibition of melanin synthesis, reduction of melanin, and inhibition of melanosome transport. The whitening raw materials in spot-removing and whitening cosmetics achieve whitening effects by inhibiting the rate-limiting enzyme tyrosinase of the melanin biosynthesis pathway, participating in the regulation of the melanin biosynthesis signaling pathway, and reducing melanin or inhibiting melanosome transport and other mechanisms of action. With the increasing market demand for spot-removing and whitening cosmetics, more and more natural active ingredients are added to the cosmetics as whitening raw materials, but there are problems such as unclear composition and missing mechanism of action. In sequence to provide a theoretical foundation for the clinical strategy of skin pigmentation prevention and treatment as well as the product development of whitening cosmetics, the action mechanisms of the existing whitening cosmetic efficacy components cosmetics are sorted out and discussed in this paper.

Key words: melanin, whitening cosmetics, tyrosinase

CLC Number:

TQ658

Ning Li, Ennian Li, Hongbo Chen, Fang Cheng, Hengfang Zou, Hongpeng Chen. Advances of functional components in whitening cosmetic[J].China Surfactant Detergent & Cosmetics, 2024, 54(1): 80-89.

Figures/Tables 10

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Advances of functional components in whitening cosmetic

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