牙膏中不同形态氟化物的固体NMR研究

doi:10.3969/j.issn.2097-2806.2023.08.013

Abstract

Abstract:

Different forms of fluoride in 38 fluoride toothpaste samples were determined by ¹⁹F solid-state nuclear magnetic resonance （¹⁹F SS-NMR）. The results show that the matching stability of different friction agents and fluoride is quite different. The soluble and free types are the main forms of fluoride in hydrated silica toothpaste, but newly generated insoluble solid calcium fluoride signal is observed in some calcium carbonate-based toothpastes. In addition to the influence of friction agents, in some toothpastes with functional ingredients such as hydroxyapatite, the formation of insoluble calcium fluoride is also observed. The formation of insoluble fluoride will reduce the amount of available fluoride in toothpaste. ¹⁹F SS-NMR has the characteristics of simple pretreatment, strong specificity and high sensitivity. It can quickly analyze the morphology of fluoride in fluoride toothpaste, and provide technical support for toothpaste formulation development and quality improvement.

Key words: toothpaste, fluoride

CLC Number:

TQ658

Zhou Lei,Cao Dongxia,Li Jiahong,Su Nafeng,Li Wenhui. Study of different forms of fluoride in toothpaste by solid state NMR[J].China Surfactant Detergent & Cosmetics, 2023, 53(8): 963-967.

Figures/Tables 11

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References 15

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种类	固体NMR化学位移（峰型）	液体NMR化学位移（峰型）^[1]
氟化钠	-223（s，br）	-122.6（s）
单氟磷酸钠	-73.6＆-76.1（d，br）	-73.0＆-74.9（d）

检测样品	氟化物和摩擦剂配方	样品数量
1	氟化钠和水合硅石	23
2	单氟磷酸钠和水合硅石	11
3	单氟磷酸钠和碳酸钙	4

Study of different forms of fluoride in toothpaste by solid state NMR

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